trans-Zeatin-d₅

Name: trans-Zeatin-d 5
Brand: MedChemExpress
SKU: HY-19700S
Rating: 4.5 (1 reviews)

Cat. No.: HY-19700S Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

trans-Zeatin-d₅ is deuterium labeled trans-Zeatin. trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.

For research use only. We do not sell to patients.

trans-Zeatin-d<sub>5</sub> Chemical Structure

trans-Zeatin-d₅ Chemical Structure

CAS No. : 72963-19-0

Size	Price	Stock	Quantity
1 mg	USD 880	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of trans-Zeatin-d₅:

trans-Zeatin In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

224.27

Formula

C₁₀H₈D₅N₅O

CAS No.

72963-19-0

Unlabeled Cas

1637-39-4

Appearance

Solid

Color

White to off-white

SMILES

OC([2H])([2H])/C(C([2H])([2H])[2H])=C/CNC1=C2C(N=CN2)=NC=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (111.47 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4589 mL	22.2946 mL	44.5891 mL
5 mM	0.8918 mL	4.4589 mL	8.9178 mL
10 mM	0.4459 mL	2.2295 mL	4.4589 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (273 KB) SDS (251 KB)

COA (249 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Li Q, et al. Endogenous trans-zeatin content in plants with different metal-accumulating ability: a field survey. Environ Sci Pollut Res Int. 2016 Dec;23(23):23422-23435. Epub 2016 Sep 9. [Content Brief]

[3]. Ji C, et al. Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes. Int J Mol Med. 2010 Aug;26(2):257-63. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.4589 mL	22.2946 mL	44.5891 mL	111.4728 mL
	5 mM	0.8918 mL	4.4589 mL	8.9178 mL	22.2946 mL
	10 mM	0.4459 mL	2.2295 mL	4.4589 mL	11.1473 mL
	15 mM	0.2973 mL	1.4863 mL	2.9726 mL	7.4315 mL
	20 mM	0.2229 mL	1.1147 mL	2.2295 mL	5.5736 mL
	25 mM	0.1784 mL	0.8918 mL	1.7836 mL	4.4589 mL
	30 mM	0.1486 mL	0.7432 mL	1.4863 mL	3.7158 mL
	40 mM	0.1115 mL	0.5574 mL	1.1147 mL	2.7868 mL
	50 mM	0.0892 mL	0.4459 mL	0.8918 mL	2.2295 mL
	60 mM	0.0743 mL	0.3716 mL	0.7432 mL	1.8579 mL
	80 mM	0.0557 mL	0.2787 mL	0.5574 mL	1.3934 mL
	100 mM	0.0446 mL	0.2229 mL	0.4459 mL	1.1147 mL