1. Anti-infection
  2. Fungal
  3. Terconazole-d4

Terconazole-d4  (Synonyms: R42470-d4)

Cat. No.: HY-B1790S Purity: ≥99.0%
COA Handling Instructions

Terconazole-d4 is the deuterium labeled Terconazole. Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.

For research use only. We do not sell to patients.

Terconazole-d<sub>4</sub> Chemical Structure

Terconazole-d4 Chemical Structure

CAS No. : 1398065-50-3

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1 mg USD 850 In-stock
5 mg USD 2150 In-stock
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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Terconazole-d4:

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Description

Terconazole-d4 is the deuterium labeled Terconazole. Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

536.49

Formula

C26H27D4Cl2N5O3

CAS No.
Unlabeled CAS

67915-31-5

Appearance

Solid

Color

White to off-white

SMILES

CC(N1CC([2H])([2H])N(C2=CC=C(OC[C@@H]3O[C@@](CN4N=CN=C4)(C5=CC=C(Cl)C=C5Cl)OC3)C=C2)C([2H])([2H])C1)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : ≥ 5 mg/mL (9.32 mM)

DMSO : ≥ 2 mg/mL (3.73 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : ≥ 1 mg/mL (1.86 mM)

DMF:PBS(pH 7.2)(1:1) : ≥ 0.5 mg/mL (0.93 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8640 mL 9.3198 mL 18.6397 mL
5 mM 0.3728 mL 1.8640 mL 3.7279 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMSO / DMF 1 mM 1.8640 mL 9.3198 mL 18.6397 mL 46.5992 mL
DMF 5 mM 0.3728 mL 1.8640 mL 3.7279 mL 9.3198 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Terconazole-d4
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HY-B1790S
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