2. Anti-infection
  3. Bacterial Antibiotic
  4. Sulfanilamide-d4

Sulfanilamide-d4  (Synonyms: Sulphanilamide-d4)

Cat. No.: HY-B0242S1 Purity: 99.99%
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Sulfanilamide-d4 is the deuterium labeled Sulfanilamide. Sulfanilamide is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.

For research use only. We do not sell to patients.

Sulfanilamide-d<sub>4</sub> Chemical Structure

Sulfanilamide-d4 Chemical Structure

CAS No. : 77435-46-2

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1 mg USD 180 In-stock
5 mg USD 580 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Sulfanilamide-d4:

Sulfanilamide-d4 Related Antibodies

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Description

Sulfanilamide-d4 is the deuterium labeled Sulfanilamide. Sulfanilamide is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sulfanilamide-d4 Related Antibodies
Molecular Weight

176.23

Formula

C6H4D4N2O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NS(=O)(C1=C([2H])C([2H])=C(C([2H])=C1[2H])N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (567.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 10 mg/mL (56.74 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.6744 mL 28.3720 mL 56.7440 mL
5 mM 1.1349 mL 5.6744 mL 11.3488 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 5.6744 mL 28.3720 mL 56.7440 mL 141.8601 mL
5 mM 1.1349 mL 5.6744 mL 11.3488 mL 28.3720 mL
10 mM 0.5674 mL 2.8372 mL 5.6744 mL 14.1860 mL
15 mM 0.3783 mL 1.8915 mL 3.7829 mL 9.4573 mL
20 mM 0.2837 mL 1.4186 mL 2.8372 mL 7.0930 mL
25 mM 0.2270 mL 1.1349 mL 2.2698 mL 5.6744 mL
30 mM 0.1891 mL 0.9457 mL 1.8915 mL 4.7287 mL
40 mM 0.1419 mL 0.7093 mL 1.4186 mL 3.5465 mL
50 mM 0.1135 mL 0.5674 mL 1.1349 mL 2.8372 mL
DMSO 60 mM 0.0946 mL 0.4729 mL 0.9457 mL 2.3643 mL
80 mM 0.0709 mL 0.3547 mL 0.7093 mL 1.7733 mL
100 mM 0.0567 mL 0.2837 mL 0.5674 mL 1.4186 mL
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Sulfanilamide-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfanilamide-d477435-46-2Sulphanilamide-d4BacterialAntibioticInhibitorinhibitorinhibit

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