1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Suberic acid-d4

Suberic acid-d4  (Synonyms: Octanedioic acid-d4)

Cat. No.: HY-W015300S Purity: 99.90%
COA Handling Instructions

Suberic acid-d4 is the deuterium labeled Suberic acid[1]. Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency[2].

For research use only. We do not sell to patients.

Suberic acid-d<sub>4</sub> Chemical Structure

Suberic acid-d4 Chemical Structure

CAS No. : 19031-57-3

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5 mg USD 30 In-stock
10 mg USD 48 In-stock
25 mg USD 85 In-stock
50 mg USD 135 In-stock
100 mg USD 215 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Suberic acid-d4 is the deuterium labeled Suberic acid[1]. Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

178.22

Formula

C8H10D4O4

CAS No.
Unlabeled CAS

Appearance

Solid

Color

Off-white to light yellow

SMILES

OC(C([2H])([2H])CCCCC([2H])([2H])C(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (561.10 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.6110 mL 28.0552 mL 56.1104 mL
5 mM 1.1222 mL 5.6110 mL 11.2221 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.6110 mL 28.0552 mL 56.1104 mL 140.2761 mL
5 mM 1.1222 mL 5.6110 mL 11.2221 mL 28.0552 mL
10 mM 0.5611 mL 2.8055 mL 5.6110 mL 14.0276 mL
15 mM 0.3741 mL 1.8703 mL 3.7407 mL 9.3517 mL
20 mM 0.2806 mL 1.4028 mL 2.8055 mL 7.0138 mL
25 mM 0.2244 mL 1.1222 mL 2.2444 mL 5.6110 mL
30 mM 0.1870 mL 0.9352 mL 1.8703 mL 4.6759 mL
40 mM 0.1403 mL 0.7014 mL 1.4028 mL 3.5069 mL
50 mM 0.1122 mL 0.5611 mL 1.1222 mL 2.8055 mL
60 mM 0.0935 mL 0.4676 mL 0.9352 mL 2.3379 mL
80 mM 0.0701 mL 0.3507 mL 0.7014 mL 1.7535 mL
100 mM 0.0561 mL 0.2806 mL 0.5611 mL 1.4028 mL
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Suberic acid-d4
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HY-W015300S
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