2. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel Neuronal Signaling
  3. Endogenous Metabolite GlyT
  4. Stearoyl-L-carnitine-d3 chloride

Stearoyl-L-carnitine-d3 chloride 

Cat. No.: HY-130466S Purity: 97.83%
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Stearoyl-L-carnitine-d3 (chloride) is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM[1][2].

For research use only. We do not sell to patients.

Stearoyl-L-carnitine-d<sub>3</sub> chloride Chemical Structure

Stearoyl-L-carnitine-d3 chloride Chemical Structure

CAS No. : 2245711-27-5

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Based on 1 publication(s) in Google Scholar

Other Forms of Stearoyl-L-carnitine-d3 chloride:

Stearoyl-L-carnitine-d3 chloride Related Antibodies

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Description

Stearoyl-L-carnitine-d3 (chloride) is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Stearoyl-L-carnitine-d3 chloride Related Antibodies
Molecular Weight

467.14

Formula

C25H47D3ClNO4
CAS No.
Unlabeled Cas

32350-57-5
Appearance

Solid

Color

White to light yellow

SMILES

CCCCCCCCCCCCCCCCCC(O[C@H](CC(O)=O)C[N+](C)(C)C([2H])([2H])[2H])=O.[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

Ethanol : ≥ 20 mg/mL (42.81 mM)

DMF : ≥ 20 mg/mL (42.81 mM)

DMSO : ≥ 14 mg/mL (29.97 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1407 mL 10.7034 mL 21.4069 mL
5 mM 0.4281 mL 2.1407 mL 4.2814 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / Ethanol / DMF 1 mM 2.1407 mL 10.7034 mL 21.4069 mL 53.5171 mL
5 mM 0.4281 mL 2.1407 mL 4.2814 mL 10.7034 mL
10 mM 0.2141 mL 1.0703 mL 2.1407 mL 5.3517 mL
15 mM 0.1427 mL 0.7136 mL 1.4271 mL 3.5678 mL
20 mM 0.1070 mL 0.5352 mL 1.0703 mL 2.6759 mL
25 mM 0.0856 mL 0.4281 mL 0.8563 mL 2.1407 mL
Ethanol / DMF 30 mM 0.0714 mL 0.3568 mL 0.7136 mL 1.7839 mL
40 mM 0.0535 mL 0.2676 mL 0.5352 mL 1.3379 mL
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Stearoyl-L-carnitine-d3 chloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Stearoyl-L-carnitine-d32245711-27-5Endogenous MetaboliteGlyTGlycine transportersInhibitorinhibitorinhibit

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