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Results for "

isoxazoline

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16730
    Sarolaner

    PF-6450567

    		 Parasite Infection
    Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide. Sarolaner is an isoxazoline compound which shows efficacy against fleas and ticks on dogs, with a LC80 value of 0.3 μg/mL against C. felis and a LC100 value of 0.003 μg/mL against O. turicata .
    Sarolaner
  • HY-16974
    Afoxolaner

    		GABA Receptor Chloride Channel Parasite Infection
    Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod .
    Afoxolaner
  • HY-156256
    Insecticidal agent 4

    		Bacterial Infection
    Insecticidal agent 4 (compound IA-8) is an aryl isoxazoline derivative with insecticidal activity against M. separate .
    Insecticidal agent 4
  • HY-106439
    BTG 1640

    ABIO-08/01

    		 Chloride Channel Neurological Disease
    BTG 1640 (ABIO-08/01) is a potent anxiolytic isoxazoline. BTG 1640 is a selective inhibitor of GABA- and glutamate-gated chloride channels .
    BTG 1640
  • HY-147180
    Dansyl-DL-valine cyclohexylammonium

    		Others Others
    Dansyl-DL-valine cyclohexylammonium is a salt form of Dansyl-DL-valine. Dansyl-DL-valine cyclohexylammonium can be used as analyte in chromatographic separation and separation column for the separation of enantiomers and diastereomers for dansyl amino acids, aromatic carboxylic acids, and isoxazolines .
    Dansyl-DL-valine cyclohexylammonium
  • HY-158185
    Isocycloseram

    		GABA Receptor Others
    Isocycloseram is an isoxazoline insecticide and acaricide widely recognized as an allosteric modulator of GABA-gated chloride channels. Isocycloseram is active against Lepidopteran, Hemiptera, Coleoptera, Thysanoptera and Diptera pests. Isocycloseram targets the invertebrate Rdl GABA receptor, but the G335M mutation in the third transmembrane domain of the Rdl GABA receptor may mediate resistance .
    Isocycloseram

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