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Results for "

TS-IN-2

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-149849

    Thymidylate Synthase Cancer
    TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 μM. TS-IN-2 induces cancer cell apoptosis and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage .
    <em>TS-IN-2</em>
  • HY-146239

    EGFR Thymidylate Synthase Cancer
    EGFR/HER2/TS-IN-2 (compound 17) is a potent EGFR/HER2 and TS (Thymidylate synthase) inhibitor, with IC50 values of 0.173, 0.125, and 1.12 μM, respectively. EGFR/HER2/TS-IN-2 shows cytotoxic activity against MDA-MB-231 cancer cell lines, with an IC50 of 1.69 µM .
    EGFR/HER<em>2</em>/<em>TS-IN-2</em>

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