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PARP10/15-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-143398
    PARP10/15-IN-1

    		PARP Cancer
    PARP10/15-IN-1 (compound 8l) is a potent inhibitor of dual inhibitor of PARP10 and PARP15, with IC50s of 160 nM and 370 nM, respectively. PARP10/15-IN-1 can be used for cancer .
    <em>PARP10/15-IN-1</em>
  • HY-148754
    PARP10-IN-3

    		PARP Cancer
    PARP10-IN-3 is a selective mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 480 nM for human PARP10. PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC50s of 1.7 μM for human PARP2 and human PARP15, respectively .
    PARP10-IN-3
  • HY-148753
    PARP10-IN-2

    		PARP Cancer
    PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 3.64 μM for human PARP10. PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC50s of 27 μM and 11 μM for human PARP2 and human PARP15, respectively .
    PARP10-IN-2
  • HY-143338
    ART-IN-1

    		PARP Cancer
    ART-IN-1 (compound 7) is a selective PARP inhibitor with IC50s of 19, 22, 2.4, >100, 1.1 µM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively .
    ART-IN-1

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