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Results for "

Fungal Inhibitor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fungal (102) Acyltransferase (4) Androgen Receptor (2) Antibiotic (24) Apoptosis (6) ATP Synthase (1) Autophagy (3) Bacterial (18) CaMK (1) Cathepsin (1) CCR (1) Cholinesterase (ChE) (1) Cytochrome P450 (19) Dengue virus (1) DNA/RNA Synthesis (1) Endogenous Metabolite (12) ERK (1) Estrogen Receptor/ERR (2) Flavivirus (1) FLT3 (1) HCV (1) HDAC (3) HIV (3) HIV Integrase (1) HIV Protease (2) HSP (3) Influenza Virus (1) Isotope-Labeled Compounds (5) Lipoxygenase (1) MAP3K (1) MEK (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (2) Na+/H+ Exchanger (NHE) (2) NO Synthase (1) Oxidative Phosphorylation (1) P-glycoprotein (1) PAI-1 (1) Parasite (10) PD-1/PD-L1 (4) PDGFR (1) Phosphatase (3) Phosphodiesterase (PDE) (1) PPAR (2) Prostaglandin Receptor (1) Ras (4) Reactive Oxygen Species (2) Src (1) STAT (2) Succinate Dehydrogenase (1) TGF-beta/Smad (1) TMV (1) Tyrosinase (1) VEGFR (2) Wnt (3)
By Research Areas:	Cancer (35) Cardiovascular Disease (1) Endocrinology (1) Infection (130) Inflammation/Immunology (14) Metabolic Disease (4) Neurological Disease (1)

By Targets:

Fungal (102)

Acyltransferase (4)

Androgen Receptor (2)

Antibiotic (24)

Apoptosis (6)

ATP Synthase (1)

Autophagy (3)

Bacterial (18)

CaMK (1)

Cathepsin (1)

CCR (1)

Cholinesterase (ChE) (1)

Cytochrome P450 (19)

Dengue virus (1)

DNA/RNA Synthesis (1)

Endogenous Metabolite (12)

ERK (1)

Estrogen Receptor/ERR (2)

Flavivirus (1)

FLT3 (1)

HCV (1)

HDAC (3)

HIV (3)

HIV Integrase (1)

HIV Protease (2)

HSP (3)

Influenza Virus (1)

Isotope-Labeled Compounds (5)

Lipoxygenase (1)

MAP3K (1)

MEK (1)

Microtubule/Tubulin (1)

Mitochondrial Metabolism (2)

Na+/H+ Exchanger (NHE) (2)

NO Synthase (1)

Oxidative Phosphorylation (1)

P-glycoprotein (1)

PAI-1 (1)

Parasite (10)

PD-1/PD-L1 (4)

PDGFR (1)

Phosphatase (3)

Phosphodiesterase (PDE) (1)

PPAR (2)

Prostaglandin Receptor (1)

Ras (4)

Reactive Oxygen Species (2)

Src (1)

STAT (2)

Succinate Dehydrogenase (1)

TGF-beta/Smad (1)

TMV (1)

Tyrosinase (1)

VEGFR (2)

Wnt (3)

By Research Areas:

Cancer (35)

Cardiovascular Disease (1)

Endocrinology (1)

Infection (130)

Inflammation/Immunology (14)

Metabolic Disease (4)

Neurological Disease (1)

150

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Fungal

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-125344

Fusarisetin A

Endogenous Metabolite Infection

Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor .
HY-N10234

Phenylpyropene A

Acyltransferase Infection

Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ of 0.8 μM .
HY-117424

Inz-4

Fungal Infection

Inz-4 is a fungal-selective inhibitor of mitochondrial cytochrome bc1, with the IC₅₀ of 0.026 μM .

Fusarisetin A	Endogenous Metabolite	Infection
Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor .

Phenylpyropene A	Acyltransferase	Infection
Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ of 0.8 μM .

Inz-4	Fungal	Infection
Inz-4 is a fungal-selective inhibitor of mitochondrial cytochrome bc1, with the IC₅₀ of 0.026 μM .

HY-N10227

Geodin	PAI-1 Antibiotic	Infection Inflammation/Immunology
Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1) .

HY-125705

Herquline A Herqueline A	Influenza Virus	Infection Cardiovascular Disease
Herquline A (Herqueline A) is a fungal piperazine alkaloid. Herquline A is a fungal metabolite that inhibits platelet aggregation and replication of the influenza virus .

HY-121051

Aleurodiscal	Fungal Antibiotic	Infection
Aleurodiscal is an *fungal* inhibitor that can be obtained from cultures of Aleurodiscus mirabilis. Aleurodiscal can be used in the study of fungal infections .

HY-B0850

Difenoconazole	Fungal	Infection
Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth .

HY-B1839

Fluazinam

Fungal Infection

Fluazinam is a broad spectrum pyridinamine fungal inhibitor.
HY-121721

Inz-5

Fungal Infection

Inz-5 is a fungal-selective mitochondrial cytochrome bc1 inhibitor. Inz-5 impairs fungal virulence and prevents the evolution of agent resistance .
HY-N10186

Dibefurin

Phosphatase Endogenous Metabolite Others

Dibefurin is a fungal metabolite that acts as an inhibitor of calcineurin phosphatase .

Fluazinam	Fungal	Infection
Fluazinam is a broad spectrum pyridinamine *fungal* inhibitor.

Inz-5	Fungal	Infection
Inz-5 is a fungal-selective mitochondrial cytochrome bc1 inhibitor. Inz-5 impairs fungal virulence and prevents the evolution of agent resistance .

Dibefurin	Phosphatase Endogenous Metabolite	Others
Dibefurin is a fungal metabolite that acts as an inhibitor of calcineurin phosphatase .

HY-B2048

Pencycuron	Fungal	Infection
Pencycuron is a benzoylurea fungicide. Pencycuron kills fungi by inhibiting the synthesis of fungal cell walls.Pencycuron can be used in research on the control of fungal diseases on crops, such as sheath blight, powdery mildew and late blight .

HY-124555

Hexamide

Benzimine
Fungal Infection

Hexamide (Benzamine) is a fungal inhibitor. Hexamide is effective against Trichophyton .
HY-N12560

Fusaramin

Mitochondrial Metabolism Infection

Fusaramin is a mitochondrial inhibitor, has antiplant pathogenic fungal activity .
HY-119976

Boscalid

Fungal Infection

Boscalid is an anti-fungal agent. Boscalid is a succinate dehydrogenase (SDH) inhibitor .
HY-116290

Zaragozic acid A

Squalestatin S1
Others Others

Zaragozic acid A is a fungal metabolite that acts as a reversible competitive inhibitor of squalene synthase .

Hexamide Benzimine	Fungal	Infection
Hexamide (Benzamine) is a *fungal* inhibitor. Hexamide is effective against Trichophyton .

Fusaramin	Mitochondrial Metabolism	Infection
Fusaramin is a mitochondrial inhibitor, has antiplant pathogenic fungal activity .

Boscalid	Fungal	Infection
Boscalid is an *anti-fungal* agent. Boscalid is a succinate dehydrogenase (SDH) inhibitor .

Zaragozic acid A Squalestatin S1	Others	Others
Zaragozic acid A is a fungal metabolite that acts as a reversible competitive inhibitor of squalene synthase .

HY-B0850R

Difenoconazole (Standard)	Fungal	Infection
Difenoconazole (Standard) is the analytical standard of Difenoconazole. This product is intended for research and analytical applications. Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth .

HY-B0105A

(+)-Ketoconazole

(+)-Ketoconazol; (+)-R 41400
Fungal Cytochrome P450 Infection

(+)-Ketoconazole ((+)-R 41400) is an imidazole anti-fungal agent, a CYP3A4 inhibitor.
HY-N3617

Coniferin

Laricin
Fungal Infection

Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization .

(+)-Ketoconazole (+)-Ketoconazol; (+)-R 41400	Fungal Cytochrome P450	Infection
(+)-Ketoconazole ((+)-R 41400) is an imidazole anti-fungal agent, a CYP3A4 inhibitor.

Coniferin Laricin	Fungal	Infection
Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization .

HY-118330

Apigeninidin chloride Gesneridin chloride; Apigenidin chloride	Fungal	Infection
Apigeninidin (Gesneridin) chloride, a 3‐deoxyanthocyanidin, is a *fungal* growth inhibitor. Apigeninidin chloride is a bioactive red biocolorant .

HY-76200

Voriconazole 5+ Cited Publications UK-109496	Fungal Bacterial	Infection Cancer
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .

HY-100527

AN2718

Fungal Infection

AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism.

AN2718	Fungal	Infection
AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism.

HY-N2519

(E)-Coniferin (E)-Laricin	Fungal	Infection
(E)-Coniferin is the isomer of Coniferin. Coniferin is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization .

HY-114518

Butenafine KP363	Fungal	Infection
Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent . Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as tinea pedis, tinea cruris, tinea versicolor .

HY-B0105

Ketoconazole 15+ Cited Publications Ketoconazol; R 41400	Fungal Cytochrome P450 Ras Bacterial	Infection Cancer
Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.

HY-N4283

Coniferyl alcohol	Fungal Endogenous Metabolite	Infection
Coniferyl alcohol is an intermediate in biosynthesis of eugenol and of stilbenoids and coumarin . Coniferyl alcohol specifically inhibits fungal growth .

HY-76200B

Voriconazole camphorsulfonate UK-109496 camphorsulfonate	Fungal Bacterial	Infection
Voriconazole (UK-109496) camphorsulfonate is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole camphorsulfonate exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .

HY-N8921

Methoxyanigorufone

2-O-Methylanigorufone
Fungal Infection

Methoxyanigorufone (compound 4) is a compound that can be isloated from Musa acuminata var. "Yangambi km 5" .

Methoxyanigorufone 2-O-Methylanigorufone	Fungal	Infection
Methoxyanigorufone (compound 4) is a compound that can be isloated from Musa acuminata var. "Yangambi km 5" .

HY-151422

Chitin synthase inhibitor 12	Fungal	Infection Cancer
Chitin synthase inhibitor 12 is a chitin synthase inhibitor. Chitin synthase inhibitor 12 shows excellent inhibitory activity with an IC₅₀ value of 0.16 mM. Chitin synthase inhibitor 12 also is a broad-spectrum antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 12 can be used for the research of invasive fungal infections (IFIs) .

HY-151420

Chitin synthase inhibitor 10	Fungal	Infection Cancer
Chitin synthase inhibitor 10 is a chitin synthase inhibitor. Chitin synthase inhibitor 10 shows excellent chitin synthase inhibitory activity with an IC₅₀ value of 0.11 mM. Chitin synthase inhibitor 10 also is an antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 10 can be used for the research of invasive fungal infections (IFIs) .

HY-139161

Penflufen	Fungal	Infection
Penflufen is a highly efficient, broad-spectrum succinate dehydrogenase inhibitor (SDHI). Penflufen can be used as a fungicide and has broad bioactivity against many fungal diseases, including potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanut and other similar fungal diseases .

HY-126765

Territrem B	Cholinesterase (ChE)	Infection Neurological Disease
Territrem B is an irreversible inhibitor of Acetylcholinesterase (AChE) inhibitor. Territrem B is also a fungal meroterpenoid that can be isolated from Aspergillus terreus .

HY-N8331

Terpendole I

Acyltransferase Endogenous Metabolite Cancer

Terpendole I, a fungal indoloditerpene, is a ACAT (acyl-CoA: cholesterol acyltransferase) inhibitor (IC₅₀=145 µM) .

Terpendole I	Acyltransferase Endogenous Metabolite	Cancer
Terpendole I, a fungal indoloditerpene, is a ACAT (acyl-CoA: cholesterol acyltransferase) inhibitor (IC₅₀=145 µM) .

HY-153671

4'-Methyl-β-naphthoflavone	Others	Infection
4'-Methyl-β-naphthoflavone is a metabolite of Naphthoflavones (benzoflavones) in fungal. Naphthoflavones are activators or inhibitors of CYP-450 .

HY-126813

Concanamycin C

Fungal Infection

Concanamycin C inhibits proliferation of mouse splenic lymphocytes. Concanamycin C exhibits antibiotic effects against fungal and yeast .

Concanamycin C	Fungal	Infection
Concanamycin C inhibits proliferation of mouse splenic lymphocytes. Concanamycin C exhibits antibiotic effects against fungal and yeast .

HY-111357

Antifungal agent 2	Fungal	Infection
Antifungal agent 2 is a broad-spectrum *fungal* inhibitor which inhibits growth of pertinent species of Candida, Cryptococcus, and Aspergillus at a concentration as low as 0.5 μg/mL.

HY-N7291

Tryprostatin A	Others	Others
Tryprostatin A is an inhibitor of the mammalian cell cycle. Tryprostatins A can be isolated from the secondary metabolites of a marine fungal strain BM939 .

HY-114521

MPO

5-(4-Methoxyphenyl)oxazole
Parasite Infection

MPO (5-(4'-Methoxyphenyl)-oxazole) is a Caenorhabditis elegans hatch and growth inhibitor that isolated from fungal culture broth .

MPO 5-(4-Methoxyphenyl)oxazole	Parasite	Infection
MPO (5-(4'-Methoxyphenyl)-oxazole) is a Caenorhabditis elegans hatch and growth inhibitor that isolated from fungal culture broth .

HY-P3042

Chymostatin	Cathepsin	Inflammation/Immunology
Chymostatin is a potent cathepsin G inhibitor. Chymostatin inhibits fungal growth when combined with other pepsin inhibitors. Chymostatin can be used for acute lung injury and pancreatitis research .

HY-76200S

Voriconazole-d3 UK-109496-d₃	Fungal	Infection
Voriconazole-d₃ is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2].

HY-103382

Arcyriaflavin A	Fungal	Infection
Arcyriaflavin A is a fungal metabolite obtained from the fungi, Nocardiopsis. Arcyriaflavin A is an inhibitor of CDK4 (IC₅₀ = 140 nM) and CaMKII (IC₅₀ = 25 nM) .

HY-125319

Amidepsine A	Acyltransferase	Metabolic Disease
Amidepsine A is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity .

HY-123777

VT-1598	Fungal	Infection Inflammation/Immunology
VT-1598 is an orally active and selective *fungal* inhibitor targeting CYP51. VT-1598 shows anti-fungal activity against Candida auris . VT-1598 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-123777A

VT-1598 tosylate	Cytochrome P450	Infection
VT-1598 tosylate is an orally active and selective *fungal* inhibitor targeting CYP51. VT-1598 tosylate shows anti-fungal activity against C. auris . VT-1598 (tosylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-76200R

Voriconazole (Standard) UK-109496 (Standard)	Fungal Bacterial	Infection Cancer
Voriconazole (Standard) is the analytical standard of Voriconazole. This product is intended for research and analytical applications. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .

HY-129295

Amidepsine D	Acyltransferase	Metabolic Disease
Amidepsine D is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity .

HY-B2004

Thifluzamide	Fungal	Infection
Thifluzamide, a broad-spectrum succinate dehydrogenase inhibitor (SDHI) fungicide, has been widely used in the controlling of a variety of fungal diseases in rice fields .

HY-N10194

P-orlandin	Parasite Endogenous Metabolite	Infection
P-orlandin, a fungal metabolite, prevents FREP1 from binding to gametocytes or ookinetes. P-orlandin effectively inhibits P. falciparum infection in mosquitoes .

HY-17006A

Caspofungin MK-0991; L-743872	Antibiotic Fungal Bacterial	Infection
Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-N8287

Oxaline	Microtubule/Tubulin	Cancer
Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase .

HY-N6781

Ophiobolin A	Phosphodiesterase (PDE)	Infection Cancer
Ophiobolin A, a fungal metabolite and a phytotoxin, is a potent and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase, with an IC₅₀ value of 9 μM. Ophiobolin A antimicrobial and anticancer activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125344

Fusarisetin A	Infection Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields	Endogenous Metabolite
Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor .

HY-N10234

Phenylpyropene A	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Acyltransferase
Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ of 0.8 μM .

HY-N10227

Geodin	Human Gut Microbiota Metabolites Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields Inflammation/Immunology	PAI-1 Antibiotic
Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1) .

HY-125705

Herquline A Herqueline A	Cardiovascular Disease Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields	Influenza Virus
Herquline A (Herqueline A) is a fungal piperazine alkaloid. Herquline A is a fungal metabolite that inhibits platelet aggregation and replication of the influenza virus .

HY-121051

Aleurodiscal	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal Antibiotic
Aleurodiscal is an *fungal* inhibitor that can be obtained from cultures of Aleurodiscus mirabilis. Aleurodiscal can be used in the study of fungal infections .

HY-N10186

Dibefurin	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Phosphatase Endogenous Metabolite
Dibefurin is a fungal metabolite that acts as an inhibitor of calcineurin phosphatase .

HY-N12560

Fusaramin	Structural Classification Alkaloids Microorganisms Pyrrole Alkaloids Source classification	Mitochondrial Metabolism
Fusaramin is a mitochondrial inhibitor, has antiplant pathogenic fungal activity .

HY-116290

Zaragozic acid A Squalestatin S1	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Others
Zaragozic acid A is a fungal metabolite that acts as a reversible competitive inhibitor of squalene synthase .

HY-N3617

Coniferin Laricin	Infection other families Microorganisms Classification of Application Fields Simple Phenylpropanols Source classification Phenylpropanoids Plants Disease Research Fields	Fungal
Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization .

HY-118330

Apigeninidin chloride Gesneridin chloride; Apigenidin chloride	Infection Anthocyans Flavonoids Sorghum bicolor (Linn.) Moench Classification of Application Fields Gramineae Source classification Phenols Polyphenols Plants Disease Research Fields	Fungal
Apigeninidin (Gesneridin) chloride, a 3‐deoxyanthocyanidin, is a *fungal* growth inhibitor. Apigeninidin chloride is a bioactive red biocolorant .

HY-N2519

(E)-Coniferin (E)-Laricin	Infection Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	Fungal
(E)-Coniferin is the isomer of Coniferin. Coniferin is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization .

HY-N4283

Coniferyl alcohol	Infection Monophenols Classification of Application Fields Simple Phenylpropanols Source classification Phenols Phenylpropanoids Endogenous metabolite Disease Research Fields	Fungal Endogenous Metabolite
Coniferyl alcohol is an intermediate in biosynthesis of eugenol and of stilbenoids and coumarin . Coniferyl alcohol specifically inhibits fungal growth .

HY-N8921

Methoxyanigorufone 2-O-Methylanigorufone	Quinones Structural Classification Source classification Musaceae Plants Naphthalene Quinones	Fungal
Methoxyanigorufone (compound 4) is a compound that can be isloated from Musa acuminata var. "Yangambi km 5" .

HY-N8331

Terpendole I	Alkaloids Microorganisms Classification of Application Fields Terpenoids Source classification Diterpenoids Disease Research Fields Indole Alkaloids Cancer	Acyltransferase Endogenous Metabolite
Terpendole I, a fungal indoloditerpene, is a ACAT (acyl-CoA: cholesterol acyltransferase) inhibitor (IC₅₀=145 µM) .

HY-126813

Concanamycin C	Structural Classification Natural Products Microorganisms Source classification	Fungal
Concanamycin C inhibits proliferation of mouse splenic lymphocytes. Concanamycin C exhibits antibiotic effects against fungal and yeast .

HY-N7291

Tryprostatin A	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Others
Tryprostatin A is an inhibitor of the mammalian cell cycle. Tryprostatins A can be isolated from the secondary metabolites of a marine fungal strain BM939 .

HY-103382

Arcyriaflavin A	Infection Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Fungal
Arcyriaflavin A is a fungal metabolite obtained from the fungi, Nocardiopsis. Arcyriaflavin A is an inhibitor of CDK4 (IC₅₀ = 140 nM) and CaMKII (IC₅₀ = 25 nM) .

HY-125319

Amidepsine A	Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Disease Research Fields	Acyltransferase
Amidepsine A is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity .

HY-76200R

Voriconazole (Standard) UK-109496 (Standard)	Microorganisms Source classification	Fungal Bacterial
Voriconazole (Standard) is the analytical standard of Voriconazole. This product is intended for research and analytical applications. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .

HY-N10194

P-orlandin	Infection Microorganisms Classification of Application Fields Source classification Coumarins Phenols Polyphenols Phenylpropanoids Disease Research Fields	Parasite Endogenous Metabolite
P-orlandin, a fungal metabolite, prevents FREP1 from binding to gametocytes or ookinetes. P-orlandin effectively inhibits P. falciparum infection in mosquitoes .

HY-N8287

Oxaline	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Microtubule/Tubulin
Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase .

HY-N6781

Ophiobolin A	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Phosphodiesterase (PDE)
Ophiobolin A, a fungal metabolite and a phytotoxin, is a potent and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase, with an IC₅₀ value of 9 μM. Ophiobolin A antimicrobial and anticancer activity .

HY-121532

(-)-Rasfonin	Monophenols Microorganisms Classification of Application Fields Source classification Phenols Disease Research Fields Cancer	Ras Apoptosis Autophagy
(-)-Rasfonin is a fungal secondary metabolite and inhibits small G proteins Ras. (-)-Rasfonin induces apoptosis, necrosis and autophagy in ACHN cells (a renal carcinoma cell line) .

HY-136767

Cladosporin	Infection Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	Fungal Antibiotic
Cladosporin is a fungal metabolite produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin completely inhibits growth of severa dermatophytes on agar medium at a concentration of 75 μg/mL .

HY-N4283A

(E)-Coniferyl alcohol	Source classification Phenols Plants Populus tremula Salicaceae	Fungal
(E)-Coniferyl alcohol is the isomer of Coniferyl alcohol. Coniferyl alcohol is an intermediate in biosynthesis of eugenol and of stilbenoids and coumarin. Coniferyl alcohol specifically inhibits fungal growth .

HY-111321

Fuscin	Quinones Structural Classification Microorganisms Classification of Application Fields Source classification Metabolic Disease Naphthalene Quinones Disease Research Fields	Oxidative Phosphorylation CCR HIV Bacterial Mitochondrial Metabolism Endogenous Metabolite
Fuscin, a fungal metabolite, CCR5 receptor antagonist with anti-HIV effects. Fuscin is a respiration and oxidative phosphorylation inhibitor, and also a mitochondrial SH-dependent transport-linked functions inhibitor .

HY-B0238

Amorolfine hydrochloride Ro 14-4767/002	Infection Classification of Application Fields Disease Research Fields	Fungal Antibiotic
Amorolfine (Ro 14-4767/002) hydrochloride is a potent *anti-fungal* agent. Amorolfine hydrochloride inhibits ergosterol biosynthesis. Amorolfine hydrochloride has the potential for the research of Neoscytalidium dimidiatum onychomycosis .

HY-N6770

Curvularin (S)-Curvularin	Infection Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Phenols Polyphenols Disease Research Disease Research Fields	NO Synthase
Curvularin, a fungal metabolite and a potent mycotoxin naturally isolated from Curvularia lunata, inhibits cytokine-induced nitric oxide synthase (iNOS), with an IC₅₀ of 9.5 µM .

HY-16944

Soraphen A (-)-Soraphen A; Soraphen A1α	Structural Classification Natural Products Microorganisms Source classification	Fungal
Soraphen A ((-)-Soraphen A; Soraphen A1α) is a polyketide fungal inhibitor that targets acetyl-CoA carboxylase (ACC1) in vivo. Soraphen A can be isolated from Myxobacter cellulosum .

HY-118427

Asterriquinol D dimethyl ether	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Parasite Endogenous Metabolite
Asterriquinol D dimethyl ether is a fungal metabolite, which can inhibit mouse myeloma NS-1 cell lines with an IC₅₀ of 28 μg/mL. Asterriquinol D dimethyl ether also inhibits *Tritrichomonas foetus* .

HY-16589

Oligomycin A Maximum Cited Publications 29 Publications Verification MCH 32	Infection Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Disease Research Fields	ATP Synthase Fungal Antibiotic
Oligomycin A (MCH 32), created by Streptomyces, acts as a mitochondrial F₀F₁-ATPase inhibitor, with a K_i of 1 μM; Oligomycin A shows anti-fungal activity.

HY-N10014

Bulnesol	Structural Classification Natural Products Cupressaceae Neocallitropsis pancheri Source classification Plants	Fungal
Bulnesol is a sesquiterpenoid that can be isolated from Salvia dorystaechas. Bulnesol inhibits the activity of Fusarium moniliforme with an EC₅₀ value of 0.6 mg/mL. Bulnesol can be used for the research of fungal infection .

HY-N3270

Methyl orsellinate	Structural Classification Natural Products Rhododendron primuliflorum Bureau & Franch. Source classification Plants Ericaceae	Fungal Lipoxygenase
Methyl orsellinate is a phytotoxic compound with antifungal activities. Methyl orsellinate is a 5-lipoxygenase inhibitor with an IC₅₀ value of 59.6 μM. Methyl orsellinate can be used for fungal infection research .

HY-N10190

Asperaculane B	Infection Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Endogenous metabolite Disease Research Fields	Parasite Endogenous Metabolite
Asperaculane B is a fungal metabolite against P. falciparum transmission with an IC₅₀ of 7.89 µM. Asperaculane B also inhibits the development of asexual P. falciparum with IC₅₀ of 3 µM, and it is nontoxic to human cells .

HY-N7330

Integracin B	Infection Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	HIV Integrase HIV
Integracin B is a potent dimeric alkyl aromatic inhibitor of HIV-1 integrase discovered from the screening of fungal extracts using an in vitro assay. Integracin B inhibits both coupled and strand transfer activity of HIV-1 integrase .

HY-N12877

Ophiobolin H	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Ophiobolin H is a fungal metabolite that can be isolated from Aspergillus ustus. Ophiobolin H inhibits growth of Bacillus subtilis cultures. Ophiobolin H induces hyperacusia in day-old chicks at rates up to 375 mg/kg .

HY-N6772

Cytochalasin E	Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields Cancer	Autophagy
Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation .

HY-N6773

Cytochalasin A	Infection Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields	HIV Protease Fungal
Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC₅₀=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives .

HY-N6748

Roquefortine C	Infection Microorganisms Classification of Application Fields Cyclopeptides Source classification Disease Research Fields	P-glycoprotein Cytochrome P450 Bacterial Endogenous Metabolite
Roquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria .

HY-W661499

Orellanine	Structural Classification Natural Products Microorganisms Source classification	Phosphatase
Orellanine is a fungal nephrotoxin. Orellanine is also a competitive inhibitor of alkaline phosphatase. Orellanine induces cell death in proximal tubular cells and in ccRCC cells. Orellanine can be used for research of clear cell renal cell carcinoma (ccRCC) .

HY-12686

5Z-7-Oxozeaenol 10+ Cited Publications FR148083; L783279; LL-Z 1640-2	Structural Classification Natural Products Monophenols Microorganisms Classification of Application Fields Source classification Phenols Inflammation/Immunology Disease Research Fields	MAP3K VEGFR Antibiotic
5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC₅₀s of 8 nM and 52 nM, respectively.

HY-N6679A

10,11-Dehydrocurvularin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Phenols Polyphenols Disease Research Anticancer Disease Research Fields	HSP TGF-beta/Smad
10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity .

HY-N0889

Ginkgetin 4 Publications Verification	Structural Classification Flavonoids Ginkgoaceae Classification of Application Fields Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba Disease Research Fields Cancer	Wnt Apoptosis Autophagy
Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC₅₀ of 5.92 μΜ .

HY-N6735

Apicidin 1 Publications Verification OSI 2040	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Anti-parasitic Disease Research Anticancer Disease Research Fields Other Antibiotics	HDAC Parasite
Apicidin (OSI 2040) is a *fungal* metabolite, acts as an orally active histone deacetylase 7/8 (HDAC7/8) inhibitor, with antiparasitic activity and a broad spectrum antiproliferative activity. Apicidin can be used for cancer research .

HY-116700

Hinnuliquinone	Structural Classification Natural Products Nepenthes mirabilis (Lour.) Druce Source classification Plants Nepenthaceae	HIV Protease HIV
Hinnuliquinone is a C2-symmetric dimeric non-peptide fungal metabolite inhibitor of HIV-1 protease. Hinnuliquinone is a bis-indolyl-2,5-dihydroxybenzoquinone pigment, that can be isolated from Nodulisphorium hinnuleum .

HY-N8537

Enfumafungin	Infection Triterpenes Structural Classification Microorganisms Classification of Application Fields Terpenoids Source classification Disease Research Fields	Fungal
Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis .

HY-B0133

Natamycin 5 Publications Verification Pimaricin	Structural Classification Preservatives Anti-inflammation/Immunoregulatory Antifungal Classification of Application Fields Source classification Disease Research Endogenous metabolite Food Research Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Fields	Fungal Endogenous Metabolite Antibiotic Bacterial
Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .

HY-N3344

Macrocarpal C	Structural Classification Source classification Phenols Polyphenols Myrtaceae Plants Eucalyptus globulus Labill.	Fungal
Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation .

HY-163113

Anticancer agent 180	Structural Classification Microorganisms Source classification Phenols	Others
Anticancer agent 180 (compound 4) is a secondary metabolite present in fungal strains and extracted through physical interaction with Streptomyces sp. Anticancer agent 180 has potential anti-tumor activity and can inhibit the migration of MDA-MB-231 breast cancer cells .

HY-N0150

Monensin sodium 15+ Cited Publications Monensin A sodium	Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics Plant agriculture research Cancer	Bacterial Antibiotic Na+/H+ Exchanger (NHE) Parasite Apoptosis Fungal Wnt
Monensin (Monensin A) sodium, an orally active antibiotic, is an ionophore that mediates Na ⁺/H ⁺ exchange. Monensin sodium is a potent Wnt signaling inhibitor. Monensin sodium causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin sodium can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects .

Cat. No.	Product Name	Chemical Structure

HY-76200S

Voriconazole-d3
Voriconazole-d₃ is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2].

HY-B0105S1

Ketoconazole-d4

Ketoconazole-d₄ is the deuterium labeled Ketoconazole. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
HY-B0105S

Ketoconazole-d8

Ketoconazole-d₈ is the deuterium labeled Ketoconazole. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.

HY-B0843S1

Metalaxyl-d6
Metalaxyl-d₆ is the deuterium labeled Metalaxyl. Metalaxyl is a fungicide that inhibits protein synthesis in fungi. Metalaxyl inhibits the growth of potato blight (P. infestans) fungal isolates from Serbian potato fields (EC50s=0.3-3.9 μg/mL).

HY-B0843S

Metalaxyl-13C6
Metalaxyl- ¹³C₆ is the ¹³C-labeled Metalaxyl. Metalaxyl is a fungicide that inhibits protein synthesis in fungi. Metalaxyl inhibits the growth of potato blight (P. infestans) fungal isolates from Serbian potato fields (EC50s=0.3-3.9 μg/mL).

HY-17006S

Caspofungin-d4 acetate
Caspofungin-d₄ (acetate) is the deuterium labeled Caspofungin diacetate[1]. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[2][3].

HY-B0846S

Dimethomorph-d8
Dimethomorph-d₈ is the deuterium labeled Dimethomorph[1]. Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 μM[2][3][4].

HY-17395S

Terbinafine-d3 hydrochloride

Terbinafine-d₃ (hydrochloride) is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-17395AS

Terbinafine-d7
Terbinafine-d₇ is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-17006AS

Caspofungin-d4
Caspofungin-d₄ (MK-0991-d₄; L-743872-d₄) is a deuterium labeled Caspofungin (HY-17006A). Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-B2033S

Pyrimethanil-13C,15N2

Pyrimethanil- ¹³C, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection[3].

HY-B0847S

Propiconazole-d7

Propiconazole-d₇ is the deuterium labeled Propiconazole. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 µM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 µg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS)[1].

HY-B0847S1

Propiconazole-d3 nitrate

Propiconazole-d₃ (nitrate) is the deuterium labeled Propiconazole nitrate. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 µM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 µg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS).

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