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Results for "

ARI 1

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139534
    ARI-1

    		ROR Apoptosis Cancer
    ARI-1 is an inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitor. ARI-1 effectively inhibits aberrant ROR1 expression, which is associated with the development of non-small cell lung cancer (NSCLC) and EGFR-TKI-induced drug resistance. ARI-1 binds to the extracellular Frizzled domain of ROR1 and regulates PI3K/AKT/mTOR signaling in a ROR1-dependent manner. ARI-1 potently inhibits NSCLC cell proliferation and migration and has antitumor activity in vivo [1] .
    <em>ARI-1</em>
  • HY-139534A
    (S)-ARI-1

    		Others Others
    (S)-ARI-1 is an S-enantiomer of ARI-1. ARI-1 is a ROR1 inhibitor and apoptosis inducer, used in NSCLC research .
    (S)-<em>ARI-1</em>
  • HY-N0309
    Soyasaponin Ba

    		Aldose Reductase Metabolic Disease
    Soyasaponin Ba is a soyasaponin isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitors (ARI) .
    Soyasaponin Ba

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