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4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine

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  • HY-154357
    4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine

    		Nucleoside Antimetabolite/Analog Cancer
    4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    4’-<em>alpha</em>-C-<em>Azido</em>-2’,3’-<em>bis</em>(O-t-<em>butyldimethylsilyl</em>)<em>uridine</em>

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