1. Others Membrane Transporter/Ion Channel Apoptosis
  2. Isotope-Labeled Compounds Proton Pump Apoptosis
  3. Rabeprazole-d3 sodium

Rabeprazole-d3 sodium  (Synonyms: LY307640-d3 sodium)

Cat. No.: HY-B0656AS1
Handling Instructions

Rabeprazole-d3 (sodium)mis the deuterium labeled Rabeprazole sodium. Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].

For research use only. We do not sell to patients.

Rabeprazole-d<sub>3</sub> sodium Chemical Structure

Rabeprazole-d3 sodium Chemical Structure

CAS No. : 1216494-11-9

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Description

Rabeprazole-d3 (sodium)mis the deuterium labeled Rabeprazole sodium. Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

384.44

Formula

C18H17D3N3NaO3S

CAS No.
Unlabeled CAS

171440-19-0

SMILES

O=S(C1=NC2=CC=CC=C2N1[Na])CC3=NC=CC(OCCCOC([2H])([2H])[2H])=C3C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Rabeprazole-d3 sodium
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HY-B0656AS1
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