2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Chemokine & Receptors
  5. C Chemokines

C Chemokines

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The C-chemokine subfamily (γ-chemokines) lacks the first and third cysteines, and thus has only hemocysteine residues in the conserved region. This family is composed of two members, XCL1 (also known as lymphotactin/Ltn/ATAC/SCYC-1/SCM1-α) and XCL2 (SCM1-β/SCYC-2). XCL1 and XCL2 are produced by activated NK cells, CD8 T cells, γδ T cells, and NK T cells. Structurally, XCL2 and XCL1 are similar, and under physiological NaCl and temperature conditions, the folding structure of monomer chemokines and the unrelated dimer state switch between[1].

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Cat. No. Product Name / Synonyms Species Source
  • HY-P7234
    Lymphotactin/XCL1 Protein, Human

    rHuLymphotactin/XCL1; ATAC; SCYC1

    		Human E. coli
    XCL1, a C class chemokine also known as Lymphotactin, is mainly produced by activated CD8+ T cells and natural killer cells. XCL1 signals by binding to the XCR1 receptor. XCL1 is involved in infectious, inflammatory and immunological diseases. Lymphotactin/XCL1 Protein, Human (HEK293, Fc-His) is produced in E. coli, and consists of 92 amino acids (G23-G114).
  • HY-P71947A
    XCL1 Protein, Rat (His)

    Xcl1; Ltn; Scyc1; Lymphotactin; C motif chemokine 1; Cytokine SCM-1; Small-inducible cytokine C1

    		Rat E. coli
    XCL1 protein attracts lymphocytes but not monocytes or neutrophils. It plays a crucial role in accumulating dendritic cells in the thymus medulla and contributes to regulatory T cell development, establishing self-tolerance. XCL1 Protein, Rat (His) is the recombinant rat-derived XCL1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of XCL1 Protein, Rat (His) is 93 a.a., with molecular weight of ~13 kDa.
  • HY-P74461
    XCL2/SCM-1 beta Protein, Human (sf9, His)

    Cytokine SCM-1 beta; C motif chemokine 2; XCL2; SCYC2

    		Human Sf9 insect cells
    XCL2 (also knowns as SCM1-β and SCYC-2) is a member of C chemokine sub-family that is highly related to XCL1. XCL2 binds and activates the G protein-coupled receptor, XCR1. XCL2 is mainly produced by activated T cells and natural killer cells. XCL2/SCM-1 beta Protein, Human (sf9, His) is produced in sf9 insect cells with a C-Terminal His-tag. It consists of 114 amino acids (M1-G114).
  • HY-P71434
    Lymphotactin/XCL1 Protein, Human (HEK293, Fc-His)

    Lymphotactin; ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1; LTN; SCYC1 and XCL1

    		Human HEK293
    XCL1, a C class chemokine also known as Lymphotactin, is mainly produced by activated CD8+ T cells and natural killer cells. XCL1 signals by binding to the XCR1 receptor. XCL1 is involved in infectious, inflammatory and immunological diseases. Lymphotactin/XCL1 Protein, Human (HEK293, Fc-His) is produced in HEK293 cells with six C-Terminal His-tags and a C-Terminal Fc-tag. It consists of 93 amino acids (V22-G114).
  • HY-P77071
    Lymphotactin/XCL1 Protein, Canine (sf9, His)

    ATAC; C motif chemokine 1; Cytokine SCM-1; SCM-1-alpha; LTN; SCYC1

    		Canine Sf9 insect cells
    XCL1, a C class chemokine also known as Lymphotactin, is mainly produced by activated CD8+ T cells and natural killer cells. XCL1 signals by binding to the XCR1 receptor. XCL1 is involved in infectious, inflammatory and immunological diseases. Lymphotactin/XCL1 Protein, Canine (sf9, His) is produced in sf9 cells with a C-Terminal His-tag. It consists of 112 amino acids (M1-T112).
  • HY-P77072
    Lymphotactin/XCL1 Protein, Cynomolgus (sf9, His)

    ATAC; C motif chemokine 1; Cytokine SCM-1; SCM-1-alpha; LTN; SCYC1

    		Cynomolgus Sf9 insect cells
    XCL1, a C class chemokine also known as Lymphotactin, is mainly produced by activated CD8+ T cells and natural killer cells. XCL1 signals by binding to the XCR1 receptor. XCL1 is involved in infectious, inflammatory and immunological diseases. Lymphotactin/XCL1 Protein, Cynomolgus (sf9, His) is produced in sf9 cells with a C-Terminal His-tag. It consists of 114 amino acids (M1-G114).
Cat. No. Product Name Effect Purity