2. Recombinant Proteins
  3. Receptor Proteins
  4. G-Protein-Coupled Receptors (GPCRs)
  5. Adhesion GPCRs

Adhesion GPCRs

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Cat. No. Product Name / Synonyms Species Source
  • HY-P75370
    CD97 Protein, Human (HEK293, hFc)

    Adhesion G protein-coupled receptor E5; CD97; ADGRE5

    		Human HEK293
    CD97, a receptor crucial for leukocyte migration, participates in adhesion and signaling during early leukocyte activation. Forming a heterodimer with a large extracellular alpha subunit and a seven-transmembrane beta subunit, CD97 interacts with complement decay-accelerating factor (DAF). The largest isoform (isoform 1) specifically engages with chondroitin sulfate, showcasing its diverse roles in cellular processes. CD97 Protein, Human (HEK293, hFc) is the recombinant human-derived CD97 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD97 Protein, Human (HEK293, hFc) is 378 a.a., with molecular weight of 100-110 kDa.
  • HY-P76961
    GPR133 Protein, Human (HEK293, His)

    Adhesion G-protein coupled receptor D1; G-protein coupled receptor 133; ADGRD1; PGR25

    		Human HEK293
    GPR133 Protein, an orphan receptor, signals through the G(s)-alpha family of G-proteins, as indicated by studies. Its protumorigenic function, particularly in glioblastoma, suggests a potential role in tumorigenesis-associated pathological processes. GPR133 Protein, Human (HEK293, His) is the recombinant human-derived GPR133 protein, expressed by HEK293 , with C-His labeled tag. The total length of GPR133 Protein, Human (HEK293, His) is 545 a.a., with molecular weight of 90-110 KDa.
  • HY-P75796
    GPR56 Protein, Human (HEK293, His)

    Adhesion G-protein coupled receptor G1; ADGRG1 NT; ADGRG1; GPR56; TM7LN4; TM7XN1

    		Human HEK293
    GPR56, a cell adhesion receptor, mediates cell-matrix adhesion in developing neurons and hematopoietic stem cells. It acts as a receptor for collagen III (COL3A1), influencing cortical development and hematopoietic stem cell maintenance. Additionally, GPR56 plays a pivotal role in cancer progression by inhibiting angiogenesis via PRKCA-mediated signaling and is essential for testis development. GPR56 Protein, Human (HEK293, His) is the recombinant human-derived GPR56 protein, expressed by HEK293, with C-His labeled tag. The total length of GPR56 Protein, Human (HEK293, His) is 317 a.a., with molecular weight of 45-70 kDa.
  • HY-P75369
    CD97 Protein, Human (HEK293, His)

    Adhesion G protein-coupled receptor E5; CD97; ADGRE5

    		Human HEK293
    CD97, a receptor crucial for leukocyte migration, participates in adhesion and signaling during early leukocyte activation. Forming a heterodimer with a large extracellular alpha subunit and a seven-transmembrane beta subunit, CD97 interacts with complement decay-accelerating factor (DAF). The largest isoform (isoform 1) specifically engages with chondroitin sulfate, showcasing its diverse roles in cellular processes. CD97 Protein, Human (HEK293, His) is the recombinant human-derived CD97 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD97 Protein, Human (HEK293, His) is 378 a.a., with molecular weight of 60-82 kDa.
  • HY-P76960
    GPR114 Protein, Human (HEK293, Fc)

    Adhesion G-protein coupled receptor G5; G-protein coupled receptor 114; ADGRG5; PGR27

    		Human HEK293
    GPR114, an adhesion G protein-coupled receptor (GPCR), crucially activates the adenylate cyclase pathway by coupling with G(s) subunit alpha. Isoform 1, displaying constitutive activity, elevates basal cyclic AMP (cAMP) levels and responds to mechanical stimulation, emphasizing GPR114's functional significance in intracellular signaling cascades and its role in cellular responses to mechanical cues. GPR114 Protein, Human (HEK293, Fc) is the recombinant human-derived GPR114 protein, expressed by HEK293, with C-hFc labeled tag. The total length of GPR114 Protein, Human (HEK293, Fc) is 163 a.a., with molecular weight of 56-63 kDa.
Cat. No. Product Name Effect Purity