1. Immunology/Inflammation
  2. COX
  3. Propyphenazone-d3

Propyphenazone-d3 is the deuterium labeled Propyphenazone. Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as proagents and selective cyclooxygenase-2 inhibitors.

For research use only. We do not sell to patients.

Propyphenazone-d<sub>3</sub> Chemical Structure

Propyphenazone-d3 Chemical Structure

CAS No. : 162935-29-7

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Based on 1 publication(s) in Google Scholar

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Description

Propyphenazone-d3 is the deuterium labeled Propyphenazone. Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as proagents and selective cyclooxygenase-2 inhibitors.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

233.32

Formula

C14H15D3N2O

CAS No.
Unlabeled CAS

479-92-5

Appearance

Solid

Color

White to off-white

SMILES

O=C1N(C2=CC=CC=C2)N(C(C)=C1C(C)C)C([2H])([2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Propyphenazone-d3
Cat. No.:
HY-A0273S
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