2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Prazosin-d8

Prazosin-d8 is the deuterium labeled Prazosin. Prazosin is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder.

For research use only. We do not sell to patients.

Prazosin-d<sub>8</sub> Chemical Structure

Prazosin-d8 Chemical Structure

CAS No. : 1006717-55-0

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1 mg USD 290 In-stock
5 mg USD 930 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Prazosin-d8:

Prazosin-d8 Related Antibodies

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Description

Prazosin-d8 is the deuterium labeled Prazosin. Prazosin is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Prazosin-d8 Related Antibodies
Molecular Weight

391.45

Formula

C19H13D8N5O4
CAS No.
Unlabeled CAS

19216-56-9
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1C([2H])([2H])C([2H])([2H])N(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)C([2H])([2H])C1([2H])[2H])C4=CC=CO4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 41.67 mg/mL (106.45 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 0.1 mg/mL (0.26 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5546 mL 12.7730 mL 25.5460 mL
5 mM 0.5109 mL 2.5546 mL 5.1092 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5546 mL 12.7730 mL 25.5460 mL 63.8651 mL
5 mM 0.5109 mL 2.5546 mL 5.1092 mL 12.7730 mL
10 mM 0.2555 mL 1.2773 mL 2.5546 mL 6.3865 mL
15 mM 0.1703 mL 0.8515 mL 1.7031 mL 4.2577 mL
20 mM 0.1277 mL 0.6387 mL 1.2773 mL 3.1933 mL
25 mM 0.1022 mL 0.5109 mL 1.0218 mL 2.5546 mL
30 mM 0.0852 mL 0.4258 mL 0.8515 mL 2.1288 mL
40 mM 0.0639 mL 0.3193 mL 0.6387 mL 1.5966 mL
50 mM 0.0511 mL 0.2555 mL 0.5109 mL 1.2773 mL
60 mM 0.0426 mL 0.2129 mL 0.4258 mL 1.0644 mL
80 mM 0.0319 mL 0.1597 mL 0.3193 mL 0.7983 mL
100 mM 0.0255 mL 0.1277 mL 0.2555 mL 0.6387 mL
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Prazosin-d8 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Prazosin-d81006717-55-0Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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