1. Metabolic Enzyme/Protease
  2. Liposome
  3. PPZ-A10

PPZ-A10 is a ionizable lipid that delivered mRNA preferentially to liver and spleen immune cells.

For research use only. We do not sell to patients.

PPZ-A10 Chemical Structure

PPZ-A10 Chemical Structure

CAS No. : 2941268-67-1

Size Price Stock Quantity
5 mg USD 140 In-stock
10 mg USD 230 In-stock
25 mg USD 460 In-stock
50 mg USD 740 In-stock
100 mg USD 1180 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

PPZ-A10 is a ionizable lipid that delivered mRNA preferentially to liver and spleen immune cells.

Molecular Weight

903.54

Formula

C56H114N6O2

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(CCN(CCCCCCCCCC)CCCCCCCCCC)NCCCN1CCN(CCCNC(CCN(CCCCCCCCCC)CCCCCCCCCC)=O)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (110.68 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1068 mL 5.5338 mL 11.0676 mL
5 mM 0.2214 mL 1.1068 mL 2.2135 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1068 mL 5.5338 mL 11.0676 mL 27.6689 mL
5 mM 0.2214 mL 1.1068 mL 2.2135 mL 5.5338 mL
10 mM 0.1107 mL 0.5534 mL 1.1068 mL 2.7669 mL
15 mM 0.0738 mL 0.3689 mL 0.7378 mL 1.8446 mL
20 mM 0.0553 mL 0.2767 mL 0.5534 mL 1.3834 mL
25 mM 0.0443 mL 0.2214 mL 0.4427 mL 1.1068 mL
30 mM 0.0369 mL 0.1845 mL 0.3689 mL 0.9223 mL
40 mM 0.0277 mL 0.1383 mL 0.2767 mL 0.6917 mL
50 mM 0.0221 mL 0.1107 mL 0.2214 mL 0.5534 mL
60 mM 0.0184 mL 0.0922 mL 0.1845 mL 0.4611 mL
80 mM 0.0138 mL 0.0692 mL 0.1383 mL 0.3459 mL
100 mM 0.0111 mL 0.0553 mL 0.1107 mL 0.2767 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PPZ-A10
Cat. No.:
HY-156857
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