1. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  2. Adrenergic Receptor Endogenous Metabolite
  3. Octopamine-d4 hydrochloride

Octopamine-d4 hydrochloride  (Synonyms: (±)-p-Octopamine-d4 hydrochloride)

Cat. No.: HY-B0528AS Purity: ≥98.0%
COA Handling Instructions

Octopamine-d4 (hydrochloride) is the deuterium labeled Octopamine hydrochloride. Octopamine ((±)-p-Octopamine) hydrochloride, a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine hydrochloride can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine hydrochloride increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure[1][2][3].

For research use only. We do not sell to patients.

Octopamine-d<sub>4</sub> hydrochloride Chemical Structure

Octopamine-d4 hydrochloride Chemical Structure

CAS No. : 1219803-62-9

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1 mg USD 300 In-stock
5 mg USD 900 In-stock
10 mg USD 1440 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Octopamine-d4 (hydrochloride) is the deuterium labeled Octopamine hydrochloride. Octopamine ((±)-p-Octopamine) hydrochloride, a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine hydrochloride can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine hydrochloride increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

192.66

Formula

C8H9D3ClNO2

CAS No.
Unlabeled CAS

770-05-9

Appearance

Solid

Color

Light brown to brown

SMILES

NC([2H])([2H])C(C1=CC=C(C=C1)O)([2H])O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (519.05 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL (259.52 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.1905 mL 25.9525 mL 51.9049 mL
5 mM 1.0381 mL 5.1905 mL 10.3810 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 5.1905 mL 25.9525 mL 51.9049 mL 129.7623 mL
5 mM 1.0381 mL 5.1905 mL 10.3810 mL 25.9525 mL
10 mM 0.5190 mL 2.5952 mL 5.1905 mL 12.9762 mL
15 mM 0.3460 mL 1.7302 mL 3.4603 mL 8.6508 mL
20 mM 0.2595 mL 1.2976 mL 2.5952 mL 6.4881 mL
25 mM 0.2076 mL 1.0381 mL 2.0762 mL 5.1905 mL
30 mM 0.1730 mL 0.8651 mL 1.7302 mL 4.3254 mL
40 mM 0.1298 mL 0.6488 mL 1.2976 mL 3.2441 mL
50 mM 0.1038 mL 0.5190 mL 1.0381 mL 2.5952 mL
60 mM 0.0865 mL 0.4325 mL 0.8651 mL 2.1627 mL
80 mM 0.0649 mL 0.3244 mL 0.6488 mL 1.6220 mL
100 mM 0.0519 mL 0.2595 mL 0.5190 mL 1.2976 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Octopamine-d4 hydrochloride
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HY-B0528AS
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