Nifursol-¹³C₆

Name: Nifursol- 13 C 6
Brand: MedChemExpress
SKU: HY-B1703S
Rating: 4.5 (1 reviews)

Cat. No.: HY-B1703S Purity: 99.60%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Nifursol-¹³C₆ is the ¹³C₆ labeled Nifursol. Nifursol is a potent and orally active veterinary antibiotic for the prevention of histomoniasis. Nifursol rapidly metabolizes to form the metabolic marker 3,5-dinitrosalicyclic acid hydrazide (DNSAH) which can persist for a long time. Nifursol is widely used for the research of Escherichia Gastroenteropathy in poultry, fowl and aquatic animal.

For research use only. We do not sell to patients.

Nifursol-<sup>13</sup>C<sub>6</sub> Chemical Structure

Nifursol-¹³C₆ Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 500	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Nifursol-¹³C₆:

Nifursol In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

371.17

Formula

C₆¹³C₆H₇N₅O₉

Unlabeled Cas

16915-70-1

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N/N=C/C1=CC=C([N+]([O-])=O)O1)[13C]2=[13CH][13C]([N+]([O-])=O)=[13CH][13C]([N+]([O-])=O)=[13C]2O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (134.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6942 mL	13.4709 mL	26.9418 mL
5 mM	0.5388 mL	2.6942 mL	5.3884 mL
10 mM	0.2694 mL	1.3471 mL	2.6942 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.60%

Select Batch:

Data Sheet (275 KB) SDS (251 KB)

COA (251 KB) HNMR (192 KB) RP-HPLC (200 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Bowen TE, et al. Effect of cupric sulfate on the prophylactic efficacy of 2-acetylamino-5nitrothiazole, nifursol and ipronidazole against histomoniasis in turkeys. Poult Sci. 1971 Nov;50(6):1668-72. [Content Brief]

[3]. Jorge Barbosa, et al.Detection, accumulation, distribution, and depletion of furaltadone and nifursol residues in poultry muscle, liver, and gizzard. J Agric Food Chem. 2011 Nov 23;59(22):11927-34. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6942 mL	13.4709 mL	26.9418 mL	67.3546 mL
	5 mM	0.5388 mL	2.6942 mL	5.3884 mL	13.4709 mL
	10 mM	0.2694 mL	1.3471 mL	2.6942 mL	6.7355 mL
	15 mM	0.1796 mL	0.8981 mL	1.7961 mL	4.4903 mL
	20 mM	0.1347 mL	0.6735 mL	1.3471 mL	3.3677 mL
	25 mM	0.1078 mL	0.5388 mL	1.0777 mL	2.6942 mL
	30 mM	0.0898 mL	0.4490 mL	0.8981 mL	2.2452 mL
	40 mM	0.0674 mL	0.3368 mL	0.6735 mL	1.6839 mL
	50 mM	0.0539 mL	0.2694 mL	0.5388 mL	1.3471 mL
	60 mM	0.0449 mL	0.2245 mL	0.4490 mL	1.1226 mL
	80 mM	0.0337 mL	0.1684 mL	0.3368 mL	0.8419 mL
	100 mM	0.0269 mL	0.1347 mL	0.2694 mL	0.6735 mL