2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. N-Methylnicotinamide-d4

N-Methylnicotinamide-d4 is the deuterium labeled N-Methylnicotinamide. N-Methylnicotinamide is an endogenous metabolite.

For research use only. We do not sell to patients.

N-Methylnicotinamide-d<sub>4</sub> Chemical Structure

N-Methylnicotinamide-d4 Chemical Structure

CAS No. : 2708278-64-0

Size Price Stock Quantity
1 mg USD 50 In-stock
5 mg USD 174 In-stock
10 mg USD 280 In-stock
25 mg USD 586 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of N-Methylnicotinamide-d4:

N-Methylnicotinamide-d4 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

N-Methylnicotinamide-d4 is the deuterium labeled N-Methylnicotinamide. N-Methylnicotinamide is an endogenous metabolite.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

N-Methylnicotinamide-d4 Related Antibodies
Molecular Weight

140.18

Formula

C7H4D4N2O
CAS No.
Unlabeled CAS

114-33-0
Appearance

Solid

Color

White to off-white

SMILES

CNC(C1=C([2H])N=C([2H])C([2H])=C1[2H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (1783.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.1337 mL 35.6684 mL 71.3369 mL
5 mM 1.4267 mL 7.1337 mL 14.2674 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (250 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.1337 mL 35.6684 mL 71.3369 mL 178.3421 mL
5 mM 1.4267 mL 7.1337 mL 14.2674 mL 35.6684 mL
10 mM 0.7134 mL 3.5668 mL 7.1337 mL 17.8342 mL
15 mM 0.4756 mL 2.3779 mL 4.7558 mL 11.8895 mL
20 mM 0.3567 mL 1.7834 mL 3.5668 mL 8.9171 mL
25 mM 0.2853 mL 1.4267 mL 2.8535 mL 7.1337 mL
30 mM 0.2378 mL 1.1889 mL 2.3779 mL 5.9447 mL
40 mM 0.1783 mL 0.8917 mL 1.7834 mL 4.4586 mL
50 mM 0.1427 mL 0.7134 mL 1.4267 mL 3.5668 mL
60 mM 0.1189 mL 0.5945 mL 1.1889 mL 2.9724 mL
80 mM 0.0892 mL 0.4459 mL 0.8917 mL 2.2293 mL
100 mM 0.0713 mL 0.3567 mL 0.7134 mL 1.7834 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

N-Methylnicotinamide-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Methylnicotinamide-d42708278-64-0Endogenous MetaboliteInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
N-Methylnicotinamide-d4
Cat. No.:
HY-124124S
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.