1. Others Immunology/Inflammation
  2. Isotope-Labeled Compounds COX
  3. Mefenamic acid-13C6

Mefenamic acid-13C6 is the 13C-labeled Mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively.

For research use only. We do not sell to patients.

Mefenamic acid-<sup>13</sup>C<sub>6</sub> Chemical Structure

Mefenamic acid-13C6 Chemical Structure

CAS No. : 1325559-19-0

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Description

Mefenamic acid-13C6 is the 13C-labeled Mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

247.24

Formula

C913C6H15NO2

CAS No.
Unlabeled CAS

61-68-7

SMILES

OC([13C]([13CH]=[13CH][13CH]=[13CH]1)=[13C]1NC2=C(C(C)=CC=C2)C)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Mefenamic acid-13C6
Cat. No.:
HY-B0574S2
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