2. Anti-infection
  3. Bacterial Antibiotic
  4. Linezolid-d3

Linezolid-d3  (Synonyms: PNU-100766-d3)

Cat. No.: HY-10394S Purity: ≥99.0%
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Linezolid-d3 is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis[1].

For research use only. We do not sell to patients.

Linezolid-d<sub>3</sub> Chemical Structure

Linezolid-d3 Chemical Structure

CAS No. : 1127120-38-0

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1 mg USD 260 In-stock
5 mg USD 650 In-stock
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50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Linezolid-d3 is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis[1].

Molecular Weight

340.36

Formula

C16H17D3FN3O4
CAS No.
Unlabeled CAS

165800-03-3
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[C@H]1CNC(C([2H])([2H])[2H])=O)N(C1)C2=CC(F)=C(N3CCOCC3)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 20 mg/mL (58.76 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 10 mg/mL (29.38 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9381 mL 14.6903 mL 29.3807 mL
5 mM 0.5876 mL 2.9381 mL 5.8761 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF / DMSO 1 mM 2.9381 mL 14.6903 mL 29.3807 mL 73.4516 mL
5 mM 0.5876 mL 2.9381 mL 5.8761 mL 14.6903 mL
10 mM 0.2938 mL 1.4690 mL 2.9381 mL 7.3452 mL
15 mM 0.1959 mL 0.9794 mL 1.9587 mL 4.8968 mL
20 mM 0.1469 mL 0.7345 mL 1.4690 mL 3.6726 mL
25 mM 0.1175 mL 0.5876 mL 1.1752 mL 2.9381 mL
DMSO 30 mM 0.0979 mL 0.4897 mL 0.9794 mL 2.4484 mL
40 mM 0.0735 mL 0.3673 mL 0.7345 mL 1.8363 mL
50 mM 0.0588 mL 0.2938 mL 0.5876 mL 1.4690 mL
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Linezolid-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Linezolid-d31127120-38-0PNU-100766-d3BacterialAntibioticInhibitorinhibitorinhibit

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