2. Others Anti-infection
  3. Isotope-Labeled Compounds Bacterial Antibiotic
  4. Levofloxacin-13C,d3

Levofloxacin-13C,d3  (Synonyms: (-)-Ofloxacin-13C,d3)

Cat. No.: HY-B0330S2 Purity: ≥98.0%
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Levofloxacin-13C,d3 is the 13C- and deuterium labeled Levofloxacin.

For research use only. We do not sell to patients.

Levofloxacin-<sup>13</sup>C,d<sub>3</sub> Chemical Structure

Levofloxacin-13C,d3 Chemical Structure

CAS No. : 1261398-33-7

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Based on 1 publication(s) in Google Scholar

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Levofloxacin-13C,d3 Related Antibodies

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Description

Levofloxacin-13C,d3 is the 13C- and deuterium labeled Levofloxacin.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[83].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Levofloxacin-13C,d3 Related Antibodies
Molecular Weight

365.38

Formula

C1713CH17D3FN3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=CC(F)=C(N3CCN(CC3)[13C]([2H])([2H])[2H])C4=C2N(C=C1C(O)=O)[C@@H](C)CO4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (27.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 5 mg/mL (13.68 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7369 mL 13.6844 mL 27.3688 mL
5 mM 0.5474 mL 2.7369 mL 5.4738 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (249 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 2.7369 mL 13.6844 mL 27.3688 mL 68.4219 mL
5 mM 0.5474 mL 2.7369 mL 5.4738 mL 13.6844 mL
10 mM 0.2737 mL 1.3684 mL 2.7369 mL 6.8422 mL
DMSO 15 mM 0.1825 mL 0.9123 mL 1.8246 mL 4.5615 mL
20 mM 0.1368 mL 0.6842 mL 1.3684 mL 3.4211 mL
25 mM 0.1095 mL 0.5474 mL 1.0948 mL 2.7369 mL
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Levofloxacin-13C,d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Levofloxacin-13C,d31261398-33-7(-)-Ofloxacin-13C,d3Isotope-Labeled CompoundsBacterialAntibioticInhibitorinhibitorinhibit

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