2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Indole-3-acetamide-d5

Indole-3-acetamide-d5 is the deuterium labeled Indole-3-acetamide[1]. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[2].

For research use only. We do not sell to patients.

Indole-3-acetamide-d<sub>5</sub> Chemical Structure

Indole-3-acetamide-d5 Chemical Structure

CAS No. : 1204700-53-7

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Based on 1 publication(s) in Google Scholar

Other Forms of Indole-3-acetamide-d5:

Indole-3-acetamide-d5 Related Antibodies

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Description

Indole-3-acetamide-d5 is the deuterium labeled Indole-3-acetamide[1]. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Indole-3-acetamide-d5 Related Antibodies
Molecular Weight

179.23

Formula

C10H5D5N2O
CAS No.
Unlabeled Cas

879-37-8
Appearance

Solid

Color

White to off-white

SMILES

[2H]C1=C([2H])C([2H])=C([2H])C2=C1NC([2H])=C2CC(N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (557.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 1.3 mg/mL (7.25 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.5794 mL 27.8971 mL 55.7942 mL
5 mM 1.1159 mL 5.5794 mL 11.1588 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 5.5794 mL 27.8971 mL 55.7942 mL 139.4856 mL
5 mM 1.1159 mL 5.5794 mL 11.1588 mL 27.8971 mL
DMSO 10 mM 0.5579 mL 2.7897 mL 5.5794 mL 13.9486 mL
15 mM 0.3720 mL 1.8598 mL 3.7196 mL 9.2990 mL
20 mM 0.2790 mL 1.3949 mL 2.7897 mL 6.9743 mL
25 mM 0.2232 mL 1.1159 mL 2.2318 mL 5.5794 mL
30 mM 0.1860 mL 0.9299 mL 1.8598 mL 4.6495 mL
40 mM 0.1395 mL 0.6974 mL 1.3949 mL 3.4871 mL
50 mM 0.1116 mL 0.5579 mL 1.1159 mL 2.7897 mL
60 mM 0.0930 mL 0.4650 mL 0.9299 mL 2.3248 mL
80 mM 0.0697 mL 0.3487 mL 0.6974 mL 1.7436 mL
100 mM 0.0558 mL 0.2790 mL 0.5579 mL 1.3949 mL
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Indole-3-acetamide-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Indole-3-acetamide-d51204700-53-7Endogenous MetaboliteInhibitorinhibitorinhibit

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