2. Gene
  3. UBE2G1 - ubiquitin conjugating enzyme E2 G1 Gene

UBE2G1 - ubiquitin conjugating enzyme E2 G1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as UBC7; E217K; UBE2G

Gene ID: 7326 | Gene type: protein coding

About UBE2G1

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:4,269,259-4,366,675 (from NCBI)

This gene has 6 transcripts (splice variants), 223 orthologues and 24 paralogues. Ubiquitous expression in esophagus (RPKM 18.3), lymph node (RPKM 16.3) and 25 other tissues.

Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating Enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008]

UBE2G1 Products(1)

mRNA Protein Name
NM_003342.5 NP_003333.1 ubiquitin-conjugating enzyme E2 G1

UBE2G1 Protein Structure

UQ_con

UQ_con: Ubiquitin-conjugating enzyme (10 - 160)

  • 0
  • 100
  • 170 a.a.
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 G1

E2 ubiquitin-conjugating enzyme G1

Recombinant UBE2G1 Proteins

Cat. No. Product Name Accession Purity
HY-P77271 UBE2G1 Protein, Human P62253 (M1-E170) ≥95%

Related Diseases

Diseases Alias
Machado-Joseph Disease

SCA3

MJD

Spinocerebellar Ataxia 3

Azorean Disease

Spinocerebellar Ataxia Type 3

Spinocerebellar Atrophy

Azorean Neurologic Disease

Spinopontine Atrophy

Nigrospinodentatal Degeneration

Spinocerebellar Atrophy Iii

Spinocerebellar Atrophy Type 3

Azorean Ataxia

Azorean Disease Of The Nervous System

Machado Disease

Nigro-Spino-Dentatal Degeneration With Nuclear Ophthalmoplegia

Disease, Machado-Joseph

Ataxia, Spinocerebellar
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15346 UBE2G1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus UBE2G1 MGD MGI:1914378
Canis familiaris UBE2G1 VGNC VGNC:48052
Rattus norvegicus UBE2G1 RGD RGD:620392
Macaca mulatta UBE2G1 VGNC VGNC:78695
Felis catus UBE2G1 VGNC VGNC:66759
Bos taurus UBE2G1 VGNC VGNC:36581
Others UBE2G1 NCBI