1. Gene
  2. MMP27 - matrix metallopeptidase 27 Gene

MMP27 - matrix metallopeptidase 27 Gene

Homo sapiens

Also known as MMP-27

Gene ID: 64066 | Gene type: protein coding

About MMP27

Cytogenetic location: 11q22.2 Genomic coordinates (GRCh38): 11:102,691,487-102,705,769 (from NCBI)

This gene has 1 transcript (splice variant), 441 orthologues and 23 paralogues. Low expression observed in reference dataset.

Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. [provided by RefSeq, Jul 2008]

MMP27 Products(1)

mRNA Protein Name
NM_022122.3 NP_071405.2 matrix metalloproteinase-27 precursor

MMP27 Protein Structure

PG_binding_1

PG_binding_1: Putative peptidoglycan binding domain (27 - 86)

Peptidase_M10

Peptidase_M10: Matrixin (106 - 261)

Hemopexin

Hemopexin: Hemopexin (285 - 326)

Hemopexin

Hemopexin: Hemopexin (330 - 370)

Hemopexin

Hemopexin: Hemopexin (376 - 421)

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  • 513 a.a.
Protein Preferred Names Protein Names

matrix metalloproteinase-27

matrix metalloprotease 27

Orthologs Information

Species Symbol Source ID
Macaca mulatta MMP27 VGNC VGNC:74749
Mus musculus MMP27 MGD MGI:3039232
Felis catus MMP27 VGNC VGNC:63538
Canis familiaris MMP27 VGNC VGNC:43286
Rattus norvegicus MMP27 RGD RGD:1306642
Bos taurus MMP27 VGNC VGNC:54886