ING4 - inhibitor of growth family member 4 Gene

Homo sapiens

Also known as my036; p29ING4

Gene ID: 51147 | Gene type: protein coding

About ING4

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:6,650,301-6,663,119 (from NCBI)

This gene has 18 transcripts (splice variants), 222 orthologues and 4 paralogues. Ubiquitous expression in thyroid (RPKM 15.7), endometrium (RPKM 14.9) and 25 other tissues.

Summary

This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008]

ING4 Products(6)

mRNA	Protein	Name
NM_001127582.2	NP_001121054.1	inhibitor of growth protein 4 isoform 9
NM_001127583.2	NP_001121055.1	inhibitor of growth protein 4 isoform 3
NM_001127584.2	NP_001121056.1	inhibitor of growth protein 4 isoform 4
NM_001127585.2	NP_001121057.1	inhibitor of growth protein 4 isoform 5
NM_001127586.2	NP_001121058.1	inhibitor of growth protein 4 isoform 6
NM_016162.4	NP_057246.2	inhibitor of growth protein 4 isoform 1

ING4 Protein Structure

ING

PHD

0
100
200
249 a.a.

Protein Preferred Names

Protein Names

inhibitor of growth protein 4

brain my036 protein

Recombinant ING4 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P74798	ING4 Protein, Human (His)	Q9UNL4-1 (M1-K249)	≥95%

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06810	ING4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ING4	VGNC	VGNC:30197
Mus musculus	ING4	MGD	MGI:107307
Macaca mulatta	ING4	VGNC	VGNC:73628
Felis catus	ING4	VGNC	VGNC:62923
Canis familiaris	ING4	VGNC	VGNC:103684
Rattus norvegicus	ING4	RGD	RGD:1309407
Others	ING4	NCBI