2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Ethylmalonic acid-d5

Ethylmalonic acid-d5 is the deuterium labeled Ethylmalonic acid. Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.

For research use only. We do not sell to patients.

Ethylmalonic acid-d<sub>5</sub> Chemical Structure

Ethylmalonic acid-d5 Chemical Structure

CAS No. : 66311-22-6

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1 mg USD 80 In-stock
5 mg USD 280 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Ethylmalonic acid-d5:

Ethylmalonic acid-d5 Related Antibodies

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Description

Ethylmalonic acid-d5 is the deuterium labeled Ethylmalonic acid. Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ethylmalonic acid-d5 Related Antibodies
Molecular Weight

137.15

Formula

C5H3D5O4
CAS No.
Unlabeled Cas

601-75-2
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C(C([2H])([2H])C([2H])([2H])[2H])C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (1822.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.2913 mL 36.4564 mL 72.9129 mL
5 mM 1.4583 mL 7.2913 mL 14.5826 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.2913 mL 36.4564 mL 72.9129 mL 182.2822 mL
5 mM 1.4583 mL 7.2913 mL 14.5826 mL 36.4564 mL
10 mM 0.7291 mL 3.6456 mL 7.2913 mL 18.2282 mL
15 mM 0.4861 mL 2.4304 mL 4.8609 mL 12.1521 mL
20 mM 0.3646 mL 1.8228 mL 3.6456 mL 9.1141 mL
25 mM 0.2917 mL 1.4583 mL 2.9165 mL 7.2913 mL
30 mM 0.2430 mL 1.2152 mL 2.4304 mL 6.0761 mL
40 mM 0.1823 mL 0.9114 mL 1.8228 mL 4.5571 mL
50 mM 0.1458 mL 0.7291 mL 1.4583 mL 3.6456 mL
60 mM 0.1215 mL 0.6076 mL 1.2152 mL 3.0380 mL
80 mM 0.0911 mL 0.4557 mL 0.9114 mL 2.2785 mL
100 mM 0.0729 mL 0.3646 mL 0.7291 mL 1.8228 mL
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Ethylmalonic acid-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ethylmalonic acid-d566311-22-6Endogenous MetaboliteInhibitorinhibitorinhibit

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