1. Others Anti-infection
  2. Isotope-Labeled Compounds Bacterial Antibiotic
  3. Cefoperazone-d5

Cefoperazone-d5 is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity[1].

For research use only. We do not sell to patients.

Cefoperazone-d<sub>5</sub> Chemical Structure

Cefoperazone-d5 Chemical Structure

CAS No. : 2410425-70-4

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1 mg USD 3100 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Cefoperazone-d5 is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity[1].

IC50 & Target

β-lactam

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

650.70

Formula

C25H22D5N9O8S2

CAS No.
Unlabeled Cas

62893-19-0

Appearance

Solid

Color

White to off-white

SMILES

OC(C1=C(CSC2=NN=NN2C)CS[C@@]([C@@H]3NC([C@@H](C4=CC=C(C=C4)O)NC(N5C(C(N(CC5)C([2H])([2H])C([2H])([2H])[2H])=O)=O)=O)=O)([H])N1C3=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (153.68 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 0.1 mg/mL (0.15 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5368 mL 7.6840 mL 15.3681 mL
5 mM 0.3074 mL 1.5368 mL 3.0736 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5368 mL 7.6840 mL 15.3681 mL 38.4202 mL
5 mM 0.3074 mL 1.5368 mL 3.0736 mL 7.6840 mL
10 mM 0.1537 mL 0.7684 mL 1.5368 mL 3.8420 mL
15 mM 0.1025 mL 0.5123 mL 1.0245 mL 2.5613 mL
20 mM 0.0768 mL 0.3842 mL 0.7684 mL 1.9210 mL
25 mM 0.0615 mL 0.3074 mL 0.6147 mL 1.5368 mL
30 mM 0.0512 mL 0.2561 mL 0.5123 mL 1.2807 mL
40 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.9605 mL
50 mM 0.0307 mL 0.1537 mL 0.3074 mL 0.7684 mL
60 mM 0.0256 mL 0.1281 mL 0.2561 mL 0.6403 mL
80 mM 0.0192 mL 0.0961 mL 0.1921 mL 0.4803 mL
100 mM 0.0154 mL 0.0768 mL 0.1537 mL 0.3842 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cefoperazone-d5
Cat. No.:
HY-B0210S
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