Transmembrane reductase CYB561D2

Definition:

Transmembrane reductase that may use ascorbate as an electron donor in the cytoplasm and transfer electrons across endoplasmic reticulum membranes to reduce monodehydro-L-ascorbate radical and iron cations Fe(3+) in the lumen of that compartment.

References:

[1]. Mariam C Recuenco, et al. Functional characterization of the recombinant human tumour suppressor 101F6 protein, a cytochrome b(561) homologue. J Biochem. 2013 Feb;153(2):233-42. [Content Brief]

[2]. Mariam C Recuenco, et al. Electron transfer reactions of candidate tumor suppressor 101F6 protein, a cytochrome b561 homologue, with ascorbate and monodehydroascorbate radical. Biochemistry. 2013 May 28;52(21):3660-8. [Content Brief]

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