2. Biology Dictionary
  3. Transmembrane protein 164

Transmembrane protein 164

Definition:

Positive regulator of ferroptosis. Selectively mediates ATG5-dependent autophagosome formation during ferroptosis, rather than during starvation, and regulates the degradation of ferritin, GPX4 and lipid droplets to increase iron accumulation and lipid peroxidation, thereby promoting ferroptotic cell death.

Biomedical Dictionary

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