2. Stem Cell/Wnt TGF-beta/Smad
  3. PKA
  4. Aplithianines A

Aplithianines A is a potent inhibitor against J-PKAcα with an IC50 of 1 μM , and inhibits wild-type PKA with an IC50 of 84 nM. Aplithianines A inhibits J-PKAcα catalytic activity by competitively binding to the ATP pocket.

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Aplithianines A Chemical Structure

Aplithianines A Chemical Structure

CAS No. : 3027425-38-0

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Aplithianines A Related Antibodies

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Description

Aplithianines A is a potent inhibitor against J-PKAcα with an IC50 of 1 μM , and inhibits wild-type PKA with an IC50 of 84 nM. Aplithianines A inhibits J-PKAcα catalytic activity by competitively binding to the ATP pocket[1].

IC50 & Target

1 μM (J-PKAcα)[1]
Molecular Weight

299.35

Formula

C13H13N7S
CAS No.
SMILES

CN1C=NC=C1C(SCC2)=CN2C3=NC=NC4=C3N=CN4
Structure Classification
Initial Source

Aplidium sp.
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Aplithianines A Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aplithianines A3027425-38-0PKAProtein kinase AAplidium sp.J-PKAcαATPInhibitorinhibitorinhibit

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