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  2. Primary Antibodies
  3. Polyclonal Antibodies
  4. SREBP1 Antibody

SREBP1 Antibody

Cat. No.: HY-P80900
COA User Guide for Antibodies

SREBP1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 122 kDa, targeting to SREBP1. It can be used for WB,ELISA assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

SREBP1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 122 kDa, targeting to SREBP1. It can be used for WB,ELISA assays with tag free, in the background of Human, Mouse, Rat.

Background

SREBP1: This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively. [provided by RefSeq, Nov 2017]

Tag

Free

Gene ID

6720

Synonyms
SREBF1; BHLHD1; SREBP1; Sterol regulatory element-binding protein 1; SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription factor 1
Molecular Weight

Predicted band size: 122 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Rabbit Polyclonal Antibody

Clonality

Polyclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

P36956

Dilution Ratio

WB: 1:500-1:1,000 ;ELISA: 1:10,000

Application

WB, ELISA

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

Synthetic peptide corresponding to Human SREBP-1.The exact sequence is proprietary to MCE.

Documentation

SREBP1 Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SREBP1 Antibody
Cat. No.:
HY-P80900
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