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  4. DLST Antibody

DLST Antibody

Cat. No.: HY-P81071
COA User Guide for Antibodies

DLST Antibody is an unconjugated, approximately 41 kDa, rabbit-derived, anti-DLST polyclonal antibody. DLST Antibody can be used for: WB, ELISA, IHC-P, IHC-F, ICC, IF, expriments in mouse and predicted: human, rat, dog, pig, cow, horse, rabbit, sheep background without labeling.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $75 In-stock
50 μL $200 In-stock
100 μL $325 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

DLST Antibody is an unconjugated, approximately 41 kDa, rabbit-derived, anti-DLST polyclonal antibody. DLST Antibody can be used for: WB, ELISA, IHC-P, IHC-F, ICC, IF, expriments in mouse and predicted: human, rat, dog, pig, cow, horse, rabbit, sheep background without labeling.

Background

The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. The complex contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). DLST (dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial), also known as DLTS or 2-oxoglutarate dehydrogenase complex component E2, is a 453 amino acid protein belonging to the 2-oxoacid dehydrogenase family. DLST covalently binds one lipoyl cofactor and participates in L-lysine degradation via the saccharopine pathway. Localized to the mitochondrion, DLST forms a 24-polypeptide structural core with octahedral symmetry. The gene encoding DLST maps to human chromosome 14q24.3 and mouse chromosome 12 D2.

Biological Activity
Rat, Rabbit, Pig, Sheep, Cow, Dog, Horse
Gene ID

1743

Synonyms
2-oxoglutarate dehydrogenase complex component E2; Dihydrolipoamide S succinyltransferase (E2 component of 2 oxo glutarate complex); Dihydrolipoamide S succinyltransferase; Dihydrolipoamide succinyltransferase component of 2 oxoglutarate dehydrogenase complex; Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Dihydrolipoyllysine residue succinyltransferase component of 2 oxoglutarate dehydrogenase complex; Dihydrolipoyllysine residue succinyltransferase component of 2 oxoglutarate dehydrogenase complex mitochondrial; Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Dlst; DLTS; E2; E2K; mitochondrial; ODO2_HUMAN; OGDC-E2.
Molecular Weight

Predicted band size: 41 kDa

Purity

Affinity Purified

Subcellular Location

Mitochondrion.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Rabbit Polyclonal Antibody

Clonality

Polyclonal

Host

Rabbit

Reactivity

Human, Mouse

SwissProt ID

P36957

Dilution Ratio

WB: 1:500-2000;ELISA: 1:5000-10000; IHC-P: 1:100-500; IHC-F: 1:100-500; ICC: 1:100-500; IF=1:100-500

Application

WB, ELISA, IHC-P, IHC-F, ICC/IF

Appearance

Liquid

Formulation

Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

KLH conjugated synthetic peptide derived from human DLST: 201-300/453

Documentation

DLST Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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DLST Antibody
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HY-P81071
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