1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. Cyclin D2 Antibody (YA789)

Cyclin D2 Antibody (YA789)

Cat. No.: HY-P80634
COA User Guide for Antibodies

Cyclin D2 Antibody (YA789) is a non-conjugated and Mouse origined monoclonal antibody about 33 kDa, targeting to Cyclin D2 (6E11). It can be used for WB assays with tag free, in the background of Human.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

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Description

Cyclin D2 Antibody (YA789) is a non-conjugated and Mouse origined monoclonal antibody about 33 kDa, targeting to Cyclin D2 (6E11). It can be used for WB assays with tag free, in the background of Human.

Background

Cyclin D2 (6E11): The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3). [provided by RefSeq, Sep 2014]

Tag

Free

Gene ID

894

Synonyms
KIAK0002.
Molecular Weight

Predicted band size: 33 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Cell Biology

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human

SwissProt ID

P30279

Dilution Ratio

WB: 1:500-1:1,000

Application

WB

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG2b

Sensitivity

Endogenous

Immunogen

Synthetic peptide corresponding to Human Cyclin D2.The exact sequence is proprietary to MCE.

Documentation

Cyclin D2 Antibody (YA789) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cyclin D2 Antibody (YA789)
Cat. No.:
HY-P80634
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