1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. AIF Antibody (YA835)

AIF Antibody (YA835)

Cat. No.: HY-P80534
COA User Guide for Antibodies

AIF Antibody (YA835) is a non-conjugated and Mouse origined monoclonal antibody about 67 kDa, targeting to AIF (8H1). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

AIF Antibody (YA835) is a non-conjugated and Mouse origined monoclonal antibody about 67 kDa, targeting to AIF (8H1). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

Background

AIF (8H1): This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015]

Tag

Free

Gene ID

9131

Synonyms
AIFM1; AIF; PDCD8; Apoptosis-inducing factor 1; mitochondrial; Programmed cell death protein 8
Molecular Weight

Predicted band size: 67 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Cell Biology

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human

SwissProt ID

O95831

Dilution Ratio

WB: 1:500-1:1,000 ;IF: 1:50-1:200

Application

WB, ICC/IF

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG2a

Sensitivity

Endogenous

Immunogen

Synthetic peptide corresponding to Human AIF.The exact sequence is proprietary to MCE.

Documentation

AIF Antibody (YA835) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
AIF Antibody (YA835)
Cat. No.:
HY-P80534
Quantity:
MCE Japan Authorized Agent: