2. Others Metabolic Enzyme/Protease
  3. Dipeptidyl Peptidase Isotope-Labeled Compounds
  4. Alogliptin-13C,d3 benzoate

Alogliptin-13C,d3 benzoate  (Synonyms: SYR-322-13C,d3 benzoate)

Cat. No.: HY-A0023AS2 Purity: 98.77%
COA Handling Instructions

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Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Alogliptin-<sup>13</sup>C,d<sub>3</sub> benzoate Chemical Structure

Alogliptin-13C,d3 benzoate Chemical Structure

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1 mg USD 1100 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Alogliptin-13C,d3 benzoate:

Alogliptin-13C,d3 benzoate Related Antibodies

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Description

Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Alogliptin-13C,d3 benzoate Related Antibodies
Molecular Weight

465.52

Formula

C2413CH24D3N5O4
Appearance

Solid

Color

White to off-white

SMILES

O=C(C=C(N1C[C@H](N)CCC1)N(C2=O)CC3=C(C#N)C=CC=C3)N2[13C]([2H])([2H])[2H].O=C(O)C4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (214.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 10 mg/mL (21.48 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1481 mL 10.7407 mL 21.4814 mL
5 mM 0.4296 mL 2.1481 mL 4.2963 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 2.1481 mL 10.7407 mL 21.4814 mL 53.7034 mL
5 mM 0.4296 mL 2.1481 mL 4.2963 mL 10.7407 mL
10 mM 0.2148 mL 1.0741 mL 2.1481 mL 5.3703 mL
15 mM 0.1432 mL 0.7160 mL 1.4321 mL 3.5802 mL
20 mM 0.1074 mL 0.5370 mL 1.0741 mL 2.6852 mL
DMSO 25 mM 0.0859 mL 0.4296 mL 0.8593 mL 2.1481 mL
30 mM 0.0716 mL 0.3580 mL 0.7160 mL 1.7901 mL
40 mM 0.0537 mL 0.2685 mL 0.5370 mL 1.3426 mL
50 mM 0.0430 mL 0.2148 mL 0.4296 mL 1.0741 mL
60 mM 0.0358 mL 0.1790 mL 0.3580 mL 0.8951 mL
80 mM 0.0269 mL 0.1343 mL 0.2685 mL 0.6713 mL
100 mM 0.0215 mL 0.1074 mL 0.2148 mL 0.5370 mL
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Alogliptin-13C,d3 benzoate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alogliptin-13C,d3SYR-322-13C,d3Dipeptidyl PeptidaseIsotope-Labeled CompoundsDPPPROTAClinkerubiquitin-proteasome systemdegradeInhibitorinhibitorinhibit

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