2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Adipic acid-d10

Adipic acid-d10 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

For research use only. We do not sell to patients.

Adipic acid-d<sub>10</sub> Chemical Structure

Adipic acid-d10 Chemical Structure

CAS No. : 25373-21-1

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5 mg USD 130 In-stock
10 mg USD 220 In-stock
25 mg USD 450 In-stock
50 mg USD 720 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Adipic acid-d10:

Adipic acid-d10 Related Antibodies

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Description

Adipic acid-d10 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Adipic acid-d10 Related Antibodies
Molecular Weight

156.20

Formula

C6D10O4
CAS No.
Unlabeled Cas

124-04-9
Appearance

Solid

Color

White to off-white

SMILES

[2H]OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C(O[2H])=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (640.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 2.86 mg/mL (18.31 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.4020 mL 32.0102 mL 64.0205 mL
5 mM 1.2804 mL 6.4020 mL 12.8041 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 6.4020 mL 32.0102 mL 64.0205 mL 160.0512 mL
5 mM 1.2804 mL 6.4020 mL 12.8041 mL 32.0102 mL
10 mM 0.6402 mL 3.2010 mL 6.4020 mL 16.0051 mL
15 mM 0.4268 mL 2.1340 mL 4.2680 mL 10.6701 mL
DMSO 20 mM 0.3201 mL 1.6005 mL 3.2010 mL 8.0026 mL
25 mM 0.2561 mL 1.2804 mL 2.5608 mL 6.4020 mL
30 mM 0.2134 mL 1.0670 mL 2.1340 mL 5.3350 mL
40 mM 0.1601 mL 0.8003 mL 1.6005 mL 4.0013 mL
50 mM 0.1280 mL 0.6402 mL 1.2804 mL 3.2010 mL
60 mM 0.1067 mL 0.5335 mL 1.0670 mL 2.6675 mL
80 mM 0.0800 mL 0.4001 mL 0.8003 mL 2.0006 mL
100 mM 0.0640 mL 0.3201 mL 0.6402 mL 1.6005 mL
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Adipic acid-d10 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adipic acid-d1025373-21-1Endogenous MetaboliteInhibitorinhibitorinhibit

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