1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Trimethoprim 3-oxide

Trimethoprim 3-oxide  (Synonyms: Trimethoprim 3-N-oxide)

Cat. No.: HY-100645
COA Handling Instructions

Triméthoprime 3-oxyde (Triméthoprime 3-N-oxyde) est le principal métabolite du triméthoprime.

Trimethoprim 3-oxide (Trimethoprim 3-N-oxide) is the primary metabolite of trimethoprim.

For research use only. We do not sell to patients.

Trimethoprim 3-oxide Chemical Structure

Trimethoprim 3-oxide Chemical Structure

CAS No. : 27653-67-4

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Description

Trimethoprim 3-oxide (Trimethoprim 3-N-oxide) is the primary metabolite of trimethoprim[1].

In Vitro

Trimethoprim 3-oxide is the primary metabolite of trimethoprim[1].
Trimethoprim 3-oxide (3-NO-TMP) is converted from trimethoprim by CYP1A1 and CYP1B1 with highest rates in human liver microsomes (HLMs). The CYP1A inhibitor α-Naphthoflavone inhibits Trimethoprim 3-oxide formation, however, other competitive P450 inhibitors has no obvious inhibition on the formation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

306.32

Formula

C14H18N4O4

CAS No.
Unlabeled Cas

Appearance

Solid

Color

White to off-white

SMILES

NC1=NC=C(CC2=CC(OC)=C(OC)C(OC)=C2)C(N)=[N+]1[O-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Trimethoprim 3-oxide Related Classifications

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Trimethoprim 3-oxide
Cat. No.:
HY-100645
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