2. Signaling Pathways
  3. Immunology/Inflammation
  4. CD28
  5. CD28 Antagonist

CD28 Antagonist

CD28 Antagonists (2):

Cat. No. Product Name Effect Purity
  • HY-P99420
    Acazicolcept
    		Antagonist 99.27%
    Acazicolcept (ALPN-101), an Fc fusion protein, is a dual inducible T cell costimulator (ICOS)/CD28 antagonist. Acazicolcept has anti-inflammatory activities.
  • HY-P1698
    Reltecimod
    		Antagonist
    Reltecimod (AB-103) is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod can be used to research necrotizing soft-tissue infections (NSTIs).