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  3. Proguanil-d6

Proguanil-d6 is the deuterium labeled Proguanil, which is a prophylactic antimalarial agent.

For research use only. We do not sell to patients.

Proguanil-d<sub>6</sub> Chemical Structure

Proguanil-d6 Chemical Structure

Size Price Stock Quantity
500 μg USD 180 In-stock

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

Proguanil-d6 is the deuterium labeled Proguanil, which is a prophylactic antimalarial agent.

IC50 & Target

Plasmodium

 

Molecular Weight

259.77

Formula

C11H10D6ClN5

Appearance

Solid

Color

White to off-white

SMILES

ClC(C=C1)=CC=C1NC(NC(NC(C([2H])([2H])[2H])C([2H])([2H])[2H])=N)=N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 3 mg/mL (11.55 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 2 mg/mL (7.70 mM)

Ethanol : ≥ 1 mg/mL (3.85 mM)

DMSO:PBS (pH 7.2) (1:10) : ≥ 0.09 mg/mL (0.35 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8496 mL 19.2478 mL 38.4956 mL
5 mM 0.7699 mL 3.8496 mL 7.6991 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.31%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMF / DMSO 1 mM 3.8496 mL 19.2478 mL 38.4956 mL 96.2390 mL
DMF / DMSO 5 mM 0.7699 mL 3.8496 mL 7.6991 mL 19.2478 mL
DMSO 10 mM 0.3850 mL 1.9248 mL 3.8496 mL 9.6239 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Proguanil-d6
Cat. No.:
HY-B0806S
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