2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Nadolol-d9

Nadolol-d9  (Synonyms: SQ-11725-d9)

Cat. No.: HY-B0804S Purity: 97.01%
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Nadolol-d9 is the deuterium labeled Nadolol. Nadolol is a non-selective and orally active β-adrenergic receptors blocker[1].

For research use only. We do not sell to patients.

Nadolol-d<sub>9</sub> Chemical Structure

Nadolol-d9 Chemical Structure

CAS No. : 94513-92-5

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1 mg USD 350 In-stock
5 mg USD 1050 In-stock
10 mg USD 1850 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Nadolol-d9 is the deuterium labeled Nadolol. Nadolol is a non-selective and orally active β-adrenergic receptors blocker[1].

Molecular Weight

318.46

Formula

C17H18D9NO4
CAS No.
Unlabeled Cas

42200-33-9
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC1C(O)CC2=C(OCC(O)CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C=CC=C2C1
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (314.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1401 mL 15.7006 mL 31.4011 mL
5 mM 0.6280 mL 3.1401 mL 6.2802 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1401 mL 15.7006 mL 31.4011 mL 78.5028 mL
5 mM 0.6280 mL 3.1401 mL 6.2802 mL 15.7006 mL
10 mM 0.3140 mL 1.5701 mL 3.1401 mL 7.8503 mL
15 mM 0.2093 mL 1.0467 mL 2.0934 mL 5.2335 mL
20 mM 0.1570 mL 0.7850 mL 1.5701 mL 3.9251 mL
25 mM 0.1256 mL 0.6280 mL 1.2560 mL 3.1401 mL
30 mM 0.1047 mL 0.5234 mL 1.0467 mL 2.6168 mL
40 mM 0.0785 mL 0.3925 mL 0.7850 mL 1.9626 mL
50 mM 0.0628 mL 0.3140 mL 0.6280 mL 1.5701 mL
60 mM 0.0523 mL 0.2617 mL 0.5234 mL 1.3084 mL
80 mM 0.0393 mL 0.1963 mL 0.3925 mL 0.9813 mL
100 mM 0.0314 mL 0.1570 mL 0.3140 mL 0.7850 mL
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Nadolol-d9 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nadolol-d994513-92-5SQ-11725-d9Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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