2. GPCR/G Protein
  3. Angiotensin Receptor
  4. Candesartan-d4

Candesartan-d4  (Synonyms: CV-11974-d4)

Cat. No.: HY-B0205S Purity: 98.17%
COA Handling Instructions

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Candesartan-d4 is the deuterium labeled Candesartan, which is an angiotensin II receptor antagonist.

For research use only. We do not sell to patients.

Candesartan-d<sub>4</sub> Chemical Structure

Candesartan-d4 Chemical Structure

CAS No. : 1346604-70-3

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1 mg USD 990 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Candesartan-d4 is the deuterium labeled Candesartan, which is an angiotensin II receptor antagonist.

Molecular Weight

444.48

Formula

C24H16D4N6O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[2H]C1=C(CN2C(C(C(O)=O)=CC=C3)=C3N=C2OCC)C([2H])=C([2H])C(C4=CC=CC=C4C5=NNN=N5)=C1[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (67.49 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 30 mg/mL (67.49 mM)

Ethanol : ≥ 3 mg/mL (6.75 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2498 mL 11.2491 mL 22.4982 mL
5 mM 0.4500 mL 2.2498 mL 4.4996 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.85%

COA (260 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMSO / DMF 1 mM 2.2498 mL 11.2491 mL 22.4982 mL 56.2455 mL
5 mM 0.4500 mL 2.2498 mL 4.4996 mL 11.2491 mL
DMSO / DMF 10 mM 0.2250 mL 1.1249 mL 2.2498 mL 5.6245 mL
15 mM 0.1500 mL 0.7499 mL 1.4999 mL 3.7497 mL
20 mM 0.1125 mL 0.5625 mL 1.1249 mL 2.8123 mL
25 mM 0.0900 mL 0.4500 mL 0.8999 mL 2.2498 mL
30 mM 0.0750 mL 0.3750 mL 0.7499 mL 1.8748 mL
40 mM 0.0562 mL 0.2812 mL 0.5625 mL 1.4061 mL
50 mM 0.0450 mL 0.2250 mL 0.4500 mL 1.1249 mL
60 mM 0.0375 mL 0.1875 mL 0.3750 mL 0.9374 mL
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Candesartan-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Candesartan-d41346604-70-3CV-11974-d4Angiotensin ReceptorInhibitorinhibitorinhibit

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