4-Hydroxybenzoic acid-d₄

Name: 4-Hydroxybenzoic acid-d 4
Brand: MedChemExpress
SKU: HY-Y0264S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-Y0264S1 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

4-Hydroxybenzoic acid-d₄ is the deuterium labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.

For research use only. We do not sell to patients.

4-Hydroxybenzoic acid-d<sub>4</sub> Chemical Structure

4-Hydroxybenzoic acid-d₄ Chemical Structure

CAS No. : 152404-47-2

Size	Price	Stock	Quantity
5 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 4-Hydroxybenzoic acid-d₄:

4-Hydroxybenzoic acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

142.15

Formula

C₇H₂D₄O₃

CAS No.

152404-47-2

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=C([2H])C([2H])=C(O)C([2H])=C1[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 120 mg/mL (844.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 1.2 mg/mL (8.44 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.0348 mL	35.1741 mL	70.3482 mL
5 mM	1.4070 mL	7.0348 mL	14.0696 mL
10 mM	0.7035 mL	3.5174 mL	7.0348 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (274 KB) SDS (251 KB)

COA (251 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Cho JY, Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull. Biosci Biotechnol Biochem. 1998 Nov;62(11):2273-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H2O / DMSO	1 mM	7.0348 mL	35.1741 mL	70.3482 mL	175.8706 mL
H2O / DMSO	5 mM	1.4070 mL	7.0348 mL	14.0696 mL	35.1741 mL
DMSO	10 mM	0.7035 mL	3.5174 mL	7.0348 mL	17.5871 mL
	15 mM	0.4690 mL	2.3449 mL	4.6899 mL	11.7247 mL
	20 mM	0.3517 mL	1.7587 mL	3.5174 mL	8.7935 mL
	25 mM	0.2814 mL	1.4070 mL	2.8139 mL	7.0348 mL
	30 mM	0.2345 mL	1.1725 mL	2.3449 mL	5.8624 mL
	40 mM	0.1759 mL	0.8794 mL	1.7587 mL	4.3968 mL
	50 mM	0.1407 mL	0.7035 mL	1.4070 mL	3.5174 mL
	60 mM	0.1172 mL	0.5862 mL	1.1725 mL	2.9312 mL
	80 mM	0.0879 mL	0.4397 mL	0.8794 mL	2.1984 mL
	100 mM	0.0703 mL	0.3517 mL	0.7035 mL	1.7587 mL