3-Nitro-L-tyrosine-¹³C₆

Name: 3-Nitro-L-tyrosine- 13 C 6
Brand: MedChemExpress
SKU: HY-113248S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-113248S1 Purity: ≥95.0%: FAQs
Data Sheet SDS COA Handling Instructions

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3-Nitro-L-tyrosine-¹³C₆ is the ¹³C labeled 3-Nitro-L-tyrosine[1]. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions[2].

For research use only. We do not sell to patients.

3-Nitro-L-tyrosine-<sup>13</sup>C<sub>6</sub> Chemical Structure

3-Nitro-L-tyrosine-¹³C₆ Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 750	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 3-Nitro-L-tyrosine-¹³C₆:

3-Nitro-L-tyrosine In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

3-Nitro-L-tyrosine-¹³C₆ is the ¹³C labeled 3-Nitro-L-tyrosine[1]. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

232.14

Formula

C₃¹³C₆H₁₀N₂O₅

Unlabeled CAS

621-44-3

Appearance

Solid

Color

Off-white to yellow

SMILES

OC([C@H](C[13C]1=[13CH][13C]([N+]([O-])=O)=[13C](O)[13CH]=[13CH]1)N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 5 mg/mL (21.54 mM; Need ultrasonic and warming)

H2O : 5 mg/mL (21.54 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.3077 mL	21.5387 mL	43.0775 mL
5 mM	0.8615 mL	4.3077 mL	8.6155 mL
10 mM	0.4308 mL	2.1539 mL	4.3077 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥95.0%

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Data Sheet (269 KB) SDS (252 KB)

COA (246 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Montoliu C, et al. 3-nitro-tyrosine as a peripheral biomarker of minimal hepatic encephalopathy in patients with liver cirrhosis. Am J Gastroenterol. 2011 Sep;106(9):1629-37. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H2O	1 mM	4.3077 mL	21.5387 mL	43.0775 mL	107.6936 mL
	5 mM	0.8615 mL	4.3077 mL	8.6155 mL	21.5387 mL
	10 mM	0.4308 mL	2.1539 mL	4.3077 mL	10.7694 mL
	15 mM	0.2872 mL	1.4359 mL	2.8718 mL	7.1796 mL
	20 mM	0.2154 mL	1.0769 mL	2.1539 mL	5.3847 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.