2'-Deoxyguanosine-¹³C₁₀,¹⁵N₅ monohydrate

Name: 2'-Deoxyguanosine- 13 C 10 , 15 N 5 monohydrate
Brand: MedChemExpress
SKU: HY-D0185S4
Rating: 4.5 (1 reviews)

Cat. No.: HY-D0185S4 Purity: 99.80%: FAQs
Data Sheet SDS COA Handling Instructions

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2'-Deoxyguanosine-¹³C₁₀,¹⁵N₅ (monohydrate) is the ¹³C and ¹⁵N labeled 2'-Deoxyguanosine monohydrate[1]. 2'-Deoxyguanosine monohydrate is an endogenous metabolite.

For research use only. We do not sell to patients.

2'-Deoxyguanosine-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>5</sub> monohydrate Chemical Structure

2'-Deoxyguanosine-¹³C₁₀,¹⁵N₅ monohydrate Chemical Structure

CAS No. : 2483830-26-6

Size	Price	Stock	Quantity
1 mg	USD 450	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 2'-Deoxyguanosine-¹³C₁₀,¹⁵N₅ monohydrate:

2'-Deoxyguanosine monohydrate In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

2'-Deoxyguanosine-¹³C₁₀,¹⁵N₅ (monohydrate) is the ¹³C and ¹⁵N labeled 2'-Deoxyguanosine monohydrate[1]. 2'-Deoxyguanosine monohydrate is an endogenous metabolite.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

300.15

Formula

¹³C₁₀H₁₅¹⁵N₅O₅

CAS No.

2483830-26-6

Unlabeled CAS

312693-72-4

Appearance

Solid

Color

White to off-white

SMILES

O=[13C]1[13C]2=[13C]([15NH][13C]([15NH2])=[15N]1)[15N]([13C@]3([H])O[13C@@H]([13C@H]([13CH2]3)O)[13CH2]O)[13CH]=[15N]2.O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (83.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3317 mL	16.6583 mL	33.3167 mL
5 mM	0.6663 mL	3.3317 mL	6.6633 mL
10 mM	0.3332 mL	1.6658 mL	3.3317 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.80%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (256 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.3317 mL	16.6583 mL	33.3167 mL	83.2917 mL
	5 mM	0.6663 mL	3.3317 mL	6.6633 mL	16.6583 mL
	10 mM	0.3332 mL	1.6658 mL	3.3317 mL	8.3292 mL
	15 mM	0.2221 mL	1.1106 mL	2.2211 mL	5.5528 mL
	20 mM	0.1666 mL	0.8329 mL	1.6658 mL	4.1646 mL
	25 mM	0.1333 mL	0.6663 mL	1.3327 mL	3.3317 mL
	30 mM	0.1111 mL	0.5553 mL	1.1106 mL	2.7764 mL
	40 mM	0.0833 mL	0.4165 mL	0.8329 mL	2.0823 mL
	50 mM	0.0666 mL	0.3332 mL	0.6663 mL	1.6658 mL
	60 mM	0.0555 mL	0.2776 mL	0.5553 mL	1.3882 mL
	80 mM	0.0416 mL	0.2082 mL	0.4165 mL	1.0411 mL