1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 17β-HSD10-IN-2

17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor,targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10),a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer.

For research use only. We do not sell to patients.

17β-HSD10-IN-2 Chemical Structure

17β-HSD10-IN-2 Chemical Structure

CAS No. : 2316765-79-2

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Description

17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor,targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10),a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer[1].

IC50 & Target

17β-HSD10[1]

Molecular Weight

363.78

Formula

C15H10ClN3O4S

CAS No.
SMILES

O=C(NC1=CC=C(C(Cl)=C1)O)NC2=NC3=CC=C(C(O)=O)C=C3S2

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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17β-HSD10-IN-2
Cat. No.:
HY-155535
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