2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. Nucleoside Antimetabolite/Analog Endogenous Metabolite
  4. 1-Methylinosine-d3

1-Methylinosine-d3  (Synonyms: N1-Methylinosine-d3)

Cat. No.: HY-113139S Purity: ≥99.0%
COA Handling Instructions

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1-Methylinosine-d3 is the deuterium labeled 1-Methylinosine. 1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA[1].

For research use only. We do not sell to patients.

1-Methylinosine-d<sub>3</sub> Chemical Structure

1-Methylinosine-d3 Chemical Structure

Size Price Stock Quantity
1 mg USD 145 In-stock
5 mg USD 430 In-stock
10 mg USD 690 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Methylinosine-d3:

1-Methylinosine-d3 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

1-Methylinosine-d3 is the deuterium labeled 1-Methylinosine. 1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1-Methylinosine-d3 Related Antibodies
Molecular Weight

285.27

Formula

C11H11D3N4O5
Unlabeled CAS

2140-73-0
Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=C(N([C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C=N2)N=CN1C([2H])([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20.83 mg/mL (73.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 15 mg/mL (52.58 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 10 mg/mL (35.05 mM)

PBS (pH 7.2) : ≥ 10 mg/mL (35.05 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5055 mL 17.5273 mL 35.0545 mL
5 mM 0.7011 mL 3.5055 mL 7.0109 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (257 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF / PBS (pH 7.2) / DMSO / DMSO 1 mM 3.5055 mL 17.5273 mL 35.0545 mL 87.6363 mL
5 mM 0.7011 mL 3.5055 mL 7.0109 mL 17.5273 mL
10 mM 0.3505 mL 1.7527 mL 3.5055 mL 8.7636 mL
15 mM 0.2337 mL 1.1685 mL 2.3370 mL 5.8424 mL
20 mM 0.1753 mL 0.8764 mL 1.7527 mL 4.3818 mL
25 mM 0.1402 mL 0.7011 mL 1.4022 mL 3.5055 mL
30 mM 0.1168 mL 0.5842 mL 1.1685 mL 2.9212 mL
DMSO / DMSO 40 mM 0.0876 mL 0.4382 mL 0.8764 mL 2.1909 mL
50 mM 0.0701 mL 0.3505 mL 0.7011 mL 1.7527 mL
DMSO 60 mM 0.0584 mL 0.2921 mL 0.5842 mL 1.4606 mL
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1-Methylinosine-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Methylinosine-d3N1-Methylinosine-d3Nucleoside Antimetabolite/AnalogEndogenous MetaboliteInhibitorinhibitorinhibit

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